Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Series Page - p. iii 5. Copyright - p. iii 6. Contributors - p. iii 7. Preface - p. xv 8. Chapter One: Hydrogen bond surrogate helices as minimal mimics of protein α-helices - p. 1 9. Chapter Two: Opportunities and challenges in the synthesis of thioamidated peptides - p. 27 10. Chapter Three: Urea based foldamers - p. 59 11. Chapter Four: Analysis of folded structure and folding thermodynamics in heterogeneous-backbone proteomimetics - p. 93 12. Chapter Five: Synthesis and study of macrocyclic β-hairpin peptides for investigating amyloid oligomers - p. 123 13. Chapter Six: Solid phase submonomer azapeptide synthesis - p. 169 14. Chapter Seven: Chloroalkene dipeptide isosteres as peptidomimetics - p. 191 15. Chapter Eight: Submonomer synthesis of sequence defined peptoids with diverse side-chains - p. 241 16. Chapter Nine: Synthesis and conformation of backbone N-aminated peptides - p. 271 17. Chapter Ten: Incorporating thioamides into proteins by native chemical ligation - p. 295 18. Chapter Eleven: The enzymology of oxazolone and thioamide synthesis in methanobactin - p. 341 19. Chapter Twelve: Mechanistic studies of non-canonical amino acid mutagenesis - p. 375 20. Chapter Thirteen: Enzyme-mediated backbone N-methylation in ribosomally encoded peptides - p. 429 21. Chapter Fourteen: Enzymatic thioamidation of peptide backbones - p. 459 22. Chapter Fifteen: Initiating protein synthesis with noncanonical monomers in vitro and in vivo - p. 495 23. Chapter Sixteen: Incorporation of backbone modifications in mRNA-displayable peptides - p. 521 24. Chapter Seventeen: Incorporation of proline analogs into recombinant proteins expressed in Escherichia coli - p. 549 25. Chapter Eighteen: Peptide backbone modifications in lanthipeptides - p. 573
Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Series Page - p. iii 5. Copyright - p. iii 6. Contributors - p. iii 7. Preface - p. xv 8. Chapter One: Hydrogen bond surrogate helices as minimal mimics of protein α-helices - p. 1 9. Chapter Two: Opportunities and challenges in the synthesis of thioamidated peptides - p. 27 10. Chapter Three: Urea based foldamers - p. 59 11. Chapter Four: Analysis of folded structure and folding thermodynamics in heterogeneous-backbone proteomimetics - p. 93 12. Chapter Five: Synthesis and study of macrocyclic β-hairpin peptides for investigating amyloid oligomers - p. 123 13. Chapter Six: Solid phase submonomer azapeptide synthesis - p. 169 14. Chapter Seven: Chloroalkene dipeptide isosteres as peptidomimetics - p. 191 15. Chapter Eight: Submonomer synthesis of sequence defined peptoids with diverse side-chains - p. 241 16. Chapter Nine: Synthesis and conformation of backbone N-aminated peptides - p. 271 17. Chapter Ten: Incorporating thioamides into proteins by native chemical ligation - p. 295 18. Chapter Eleven: The enzymology of oxazolone and thioamide synthesis in methanobactin - p. 341 19. Chapter Twelve: Mechanistic studies of non-canonical amino acid mutagenesis - p. 375 20. Chapter Thirteen: Enzyme-mediated backbone N-methylation in ribosomally encoded peptides - p. 429 21. Chapter Fourteen: Enzymatic thioamidation of peptide backbones - p. 459 22. Chapter Fifteen: Initiating protein synthesis with noncanonical monomers in vitro and in vivo - p. 495 23. Chapter Sixteen: Incorporation of backbone modifications in mRNA-displayable peptides - p. 521 24. Chapter Seventeen: Incorporation of proline analogs into recombinant proteins expressed in Escherichia coli - p. 549 25. Chapter Eighteen: Peptide backbone modifications in lanthipeptides - p. 573
