Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.
1. Chapter 1. Introduction and overview of cancer precision medicine - p. 1 2. Chapter 2. From data to knowledge: an introduction to biomedical informatics - p. 13 3. Chapter 3. The functional genome: epigenetics and epigenomics - p. 29 4. Chapter 4. Clinical decision support and molecular tumor boards - p. 55 5. Chapter 5. Family health history and health risk assessment in oncology - p. 71 6. Chapter 6. Lymphomas: molecular subsets and advances in therapeutics - p. 85 7. Chapter 7. Precision medicine in myeloid neoplasms/acute leukemias - p. 103 8. Chapter 8. Lung cancer - p. 123 9. Chapter 9. Breast cancer - p. 163 10. Chapter 10. Epithelial ovarian cancer - p. 173 11. Chapter 11. Endometrial cancer - p. 191 12. Chapter 12. Colorectal cancer - p. 205 13. Chapter 13. Hepatic and bile duct cancers - p. 217 14. Chapter 14. Biomarker-directed therapy for pancreatic cancer - p. 239 15. Chapter 15. Esophageal and gastric cancer - p. 255 16. Chapter 16. Prostate Cancer - p. 277 17. Chapter 17. Genomics and precision medicine: kidney cancer - p. 285 18. Chapter 18. Head and neck squamous cell carcinoma - p. 297 19. Chapter 19. Melanoma - p. 319 20. Chapter 20. Precision cancer immunotherapy - p. 333 21. Index - p. 347
Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.
1. Chapter 1. Introduction and overview of cancer precision medicine - p. 1 2. Chapter 2. From data to knowledge: an introduction to biomedical informatics - p. 13 3. Chapter 3. The functional genome: epigenetics and epigenomics - p. 29 4. Chapter 4. Clinical decision support and molecular tumor boards - p. 55 5. Chapter 5. Family health history and health risk assessment in oncology - p. 71 6. Chapter 6. Lymphomas: molecular subsets and advances in therapeutics - p. 85 7. Chapter 7. Precision medicine in myeloid neoplasms/acute leukemias - p. 103 8. Chapter 8. Lung cancer - p. 123 9. Chapter 9. Breast cancer - p. 163 10. Chapter 10. Epithelial ovarian cancer - p. 173 11. Chapter 11. Endometrial cancer - p. 191 12. Chapter 12. Colorectal cancer - p. 205 13. Chapter 13. Hepatic and bile duct cancers - p. 217 14. Chapter 14. Biomarker-directed therapy for pancreatic cancer - p. 239 15. Chapter 15. Esophageal and gastric cancer - p. 255 16. Chapter 16. Prostate Cancer - p. 277 17. Chapter 17. Genomics and precision medicine: kidney cancer - p. 285 18. Chapter 18. Head and neck squamous cell carcinoma - p. 297 19. Chapter 19. Melanoma - p. 319 20. Chapter 20. Precision cancer immunotherapy - p. 333 21. Index - p. 347
