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Handbook of Neural Engineering: A Modern Approach provides a comprehensive overview of the field from biology to recent technological advances through an interdisciplinary lens. The book is divided into three sections: 1) Biological Considerations for Neural Engineering, 2) Neural Engineering Strategies, and 3) Emerging Technologies for Neural Engineering. It provides the first comprehensive text that addresses this combination of subjects. Neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Multiple Sclerosis, represent an enormous healthcare burden, and many of these diseases lack true cures, making it imperative to study the biological systems that become disordered to understand potential treatment options. This book covers the basic neurobiology and physiology, common neural engineering strategies, and emerging technologies in this field. It is designed to support an upper year/graduate elective course in neural engineering, and will provide a foundational overview of the field for interdisciplinary researchers, clinicians, engineers, and industry professionals. The handbook provides readers with a strong base in both biological and engineering principles along with the concepts necessary to implement solutions using Neural Engineering.

  • Includes coverage of foundational concepts of the fast-moving field of Neural Engineering, from overview and structure of the nervous system, cellular biology of the nervous system, extracellular matrix of the nervous system, role of the immune system in the nervous system, disease states of the nervous system, and the effects of trauma and chronic pain on the nervous system
  • Provides readers with understanding of Neural Engineering strategies, in key areas such as imagining, examining nervous system function, neural interfaces, Brain-Computer Interfaces, neural prostheses, neurorobotics, and neural tissue engineering
  • Includes a complete section on emerging technologies for neural engineering applications, such as optogenetics, gene editing, brain organoids, and modeling with organ-on-a-chip systems

1. 1 Introduction to neural engineering - p. 1 2. 2 Overview of the structure and function of the nervous system - p. 17 3. 3 Cellular biology of the central nervous system - p. 49 4. 4 Extracellular matrix of the nervous system - p. 97 5. 5 The immune system and its role in the nervous system - p. 149 6. 6 Modulating disease states of the central nervous system: Outcomes of neuromodulation on microglia - p. 179 7. 7 The effect of traumatic injuries on the nervous system - p. 231 8. 8 Chronic pain as a neurological disease and neural engineering strategies for its management - p. 271 9. 9 An overview of noninvasive imaging strategies in neural engineering - p. 301 10. 10 Brain-computer interface - p. 351 11. 11 Neuroprosthetics - p. 389 12. 12 Neural tissue engineering - p. 413 13. 13 Optogenetics for neural tissue engineering applications - p. 479 14. 14 Neuroengineering: History, modeling, and deliverables - p. 505 15. 15 Recent developments in 3D bioprinting for neural tissue engineering - p. 549 16. 16 Maximizing the utility of brain organoid models and overcoming their perceived limitations - p. 593 17. 17 Modeling the synapse and neuromuscular junction using organ-on-a-chip technology - p. 625 18. 1: Introduction - p. 625 19. 2: Synapse- and NMJ-on-a-chip: Design and fabrication - p. 630 20. 3: Applications of synapse and NMJ chips - p. 633 21. 4: Challenges and future directions - p. 637 22. Index - p. 645

Descripcion
Descripción

Handbook of Neural Engineering: A Modern Approach provides a comprehensive overview of the field from biology to recent technological advances through an interdisciplinary lens. The book is divided into three sections: 1) Biological Considerations for Neural Engineering, 2) Neural Engineering Strategies, and 3) Emerging Technologies for Neural Engineering. It provides the first comprehensive text that addresses this combination of subjects. Neurodegenerative diseases, including Alzheimer’s, Parkinson’s and Multiple Sclerosis, represent an enormous healthcare burden, and many of these diseases lack true cures, making it imperative to study the biological systems that become disordered to understand potential treatment options. This book covers the basic neurobiology and physiology, common neural engineering strategies, and emerging technologies in this field. It is designed to support an upper year/graduate elective course in neural engineering, and will provide a foundational overview of the field for interdisciplinary researchers, clinicians, engineers, and industry professionals. The handbook provides readers with a strong base in both biological and engineering principles along with the concepts necessary to implement solutions using Neural Engineering.

  • Includes coverage of foundational concepts of the fast-moving field of Neural Engineering, from overview and structure of the nervous system, cellular biology of the nervous system, extracellular matrix of the nervous system, role of the immune system in the nervous system, disease states of the nervous system, and the effects of trauma and chronic pain on the nervous system
  • Provides readers with understanding of Neural Engineering strategies, in key areas such as imagining, examining nervous system function, neural interfaces, Brain-Computer Interfaces, neural prostheses, neurorobotics, and neural tissue engineering
  • Includes a complete section on emerging technologies for neural engineering applications, such as optogenetics, gene editing, brain organoids, and modeling with organ-on-a-chip systems

1. 1 Introduction to neural engineering - p. 1 2. 2 Overview of the structure and function of the nervous system - p. 17 3. 3 Cellular biology of the central nervous system - p. 49 4. 4 Extracellular matrix of the nervous system - p. 97 5. 5 The immune system and its role in the nervous system - p. 149 6. 6 Modulating disease states of the central nervous system: Outcomes of neuromodulation on microglia - p. 179 7. 7 The effect of traumatic injuries on the nervous system - p. 231 8. 8 Chronic pain as a neurological disease and neural engineering strategies for its management - p. 271 9. 9 An overview of noninvasive imaging strategies in neural engineering - p. 301 10. 10 Brain-computer interface - p. 351 11. 11 Neuroprosthetics - p. 389 12. 12 Neural tissue engineering - p. 413 13. 13 Optogenetics for neural tissue engineering applications - p. 479 14. 14 Neuroengineering: History, modeling, and deliverables - p. 505 15. 15 Recent developments in 3D bioprinting for neural tissue engineering - p. 549 16. 16 Maximizing the utility of brain organoid models and overcoming their perceived limitations - p. 593 17. 17 Modeling the synapse and neuromuscular junction using organ-on-a-chip technology - p. 625 18. 1: Introduction - p. 625 19. 2: Synapse- and NMJ-on-a-chip: Design and fabrication - p. 630 20. 3: Applications of synapse and NMJ chips - p. 633 21. 4: Challenges and future directions - p. 637 22. Index - p. 645

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