Harnessing Quorum Quenching for Disease Management explores the process of quorum quenching in disrupting bacterial cell communication and how this mechanism can be utilized in the medical field. This book provides a detailed overview of quorum quenching and quorum sensing, delving into the key aspects of this process including the enzymatic mechanisms and methods available to study these. It covers quorum quenching applications, including the regulation of virulence factors, antimicrobial resistance and disease treatment, and the use of quorum quenching bacteria for medical intervention. It also considers genetically modified organisms to produce quorum quenching enzymes, nanomaterials for optimizing quorum quenching, in silico technology and the impact of synthetic biology, closing with a discussion of the current limitations and future prospects for this field. This book is an ideal reference for researchers and advanced students with an interest in quorum quenching and quorum sensing working across a range of fields, including microbiology, cell biology, biomedicine, biochemistry, biotechnology and related areas.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Part I: Understanding quorum quenching - p. 1 8. Chapter 1. Quorum sensing and quorum quenching: a brief review - p. 3 9. Chapter 2. Quorum sensing and quenching: key mechanisms and applications - p. 21 10. Chapter 3. Methods to study quorum quenching - p. 69 11. Chapter 4. Quorum sensing inhibitors from natural sources - p. 81 12. Chapter 5. Mechanistic insights into quorum quenching - p. 99 13. Part II: Quorum quenching applications - p. 115 14. Chapter 6. Inhibiting quorum sensing for antimicrobial resistance - p. 117 15. Chapter 7. Harnessing quorum sensing for disease management - p. 137 16. Chapter 8. Genetically modified organisms to produce quorum quenching enzymes - p. 153 17. Chapter 9. Quorum quenching bacteria and their application in the medical field - p. 177 18. Chapter 10. Quorum quenching for biocontrol of plant diseases - p. 201 19. Part III: Quorum quenching: new technologies, limitation and future prospects - p. 225 20. Chapter 11. Application of Nanomaterials for quorum quenching - p. 227 21. Chapter 12. In silico technologies and synthetic biology role in quorum quenching - p. 243 22. Chapter 13. Main limitations and future prospects of quorum quenching strategies - p. 257 23. Chapter 14. Synthesis and applications of nanomaterials for quorum quenching - p. 271 24. Chapter 15. Quorum quenching for virulence attenuation of agricultural pathogens: a review - p. 283 25. Index - p. 305
Harnessing Quorum Quenching for Disease Management explores the process of quorum quenching in disrupting bacterial cell communication and how this mechanism can be utilized in the medical field. This book provides a detailed overview of quorum quenching and quorum sensing, delving into the key aspects of this process including the enzymatic mechanisms and methods available to study these. It covers quorum quenching applications, including the regulation of virulence factors, antimicrobial resistance and disease treatment, and the use of quorum quenching bacteria for medical intervention. It also considers genetically modified organisms to produce quorum quenching enzymes, nanomaterials for optimizing quorum quenching, in silico technology and the impact of synthetic biology, closing with a discussion of the current limitations and future prospects for this field. This book is an ideal reference for researchers and advanced students with an interest in quorum quenching and quorum sensing working across a range of fields, including microbiology, cell biology, biomedicine, biochemistry, biotechnology and related areas.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Part I: Understanding quorum quenching - p. 1 8. Chapter 1. Quorum sensing and quorum quenching: a brief review - p. 3 9. Chapter 2. Quorum sensing and quenching: key mechanisms and applications - p. 21 10. Chapter 3. Methods to study quorum quenching - p. 69 11. Chapter 4. Quorum sensing inhibitors from natural sources - p. 81 12. Chapter 5. Mechanistic insights into quorum quenching - p. 99 13. Part II: Quorum quenching applications - p. 115 14. Chapter 6. Inhibiting quorum sensing for antimicrobial resistance - p. 117 15. Chapter 7. Harnessing quorum sensing for disease management - p. 137 16. Chapter 8. Genetically modified organisms to produce quorum quenching enzymes - p. 153 17. Chapter 9. Quorum quenching bacteria and their application in the medical field - p. 177 18. Chapter 10. Quorum quenching for biocontrol of plant diseases - p. 201 19. Part III: Quorum quenching: new technologies, limitation and future prospects - p. 225 20. Chapter 11. Application of Nanomaterials for quorum quenching - p. 227 21. Chapter 12. In silico technologies and synthetic biology role in quorum quenching - p. 243 22. Chapter 13. Main limitations and future prospects of quorum quenching strategies - p. 257 23. Chapter 14. Synthesis and applications of nanomaterials for quorum quenching - p. 271 24. Chapter 15. Quorum quenching for virulence attenuation of agricultural pathogens: a review - p. 283 25. Index - p. 305
