For this issue, Dr. Michael Lim of Johns Hopkins and Dr. Isaac Yang of UCSF team up to deliver a packed issue on the latest developments in Immunotherapy. The issue covers hot topics such as immunostimulants, Passive Antibody Mediated Immunotherapy, Clinical Applications of A Peptide Based Vaccine, Challenges for Clinical Design of Immunotherapy Trials, The EGFRv3 Peptide Vaccine, Stem Cell Therapy and Dendritic Cell Vaccines, Dendritic Glioma Fusion Vaccine, Adoptive Cellular Immunotherapy, Virus Mediated Immunotherapy, and so much more.
1. Cover - p. 1 2. Contents - p. 2 3. Forthcoming issues - p. 3 4. Preface - p. 4 5. Biologic Principles of Immunotherapy for Malignant Gliomas - p. 5 6. Mechanisms of Local Immunoresistance in Glioma - p. 18 7. Glioblastoma-Derived Mechanisms of Systemic Immunosuppression - p. 29 8. Microglia and Central Nervous System Immunity - p. 38 9. Immunostimulants for Malignant Gliomas - p. 46 10. Passive Antibody-Mediated Immunotherapy for the Treatment of Malignant Gliomas - p. 56 11. Interferon-gamma in Brain Tumor Immunotherapy - p. 63 12. The Epidermal Growth Factor Variant III Peptide Vaccine for Treatment of Malignant Gliomas - p. 68 13. Clinical Applications of a Peptide-Based Vaccine for Glioblastoma - p. 74 14. Heat Shock Proteins in Glioblastomas - p. 86 15. The Role of Tregs in Glioma-Mediated Immunosuppression: Potential Target for Intervention - p. 97 16. Dendritic Cell Vaccines for Brain Tumors - p. 107 17. Glioma Stem Cell Research for the Development of Immunotherapy - p. 118 18. Virally Mediated Immunotherapy for Brain Tumors - p. 125 19. Distinguishing Glioma Recurrence from Treatment Effect After Radiochemotherapy and Immunotherapy - p. 134 20. Immunotherapy Combined with Chemotherapy in the Treatment of Tumors - p. 138 21. Monitoring Immune Responses After Glioma Vaccine Immunotherapy - p. 145 22. Challenges in Clinical Design of Immunotherapy Trials for Malignant Glioma - p. 149 23. Index - p. 160
For this issue, Dr. Michael Lim of Johns Hopkins and Dr. Isaac Yang of UCSF team up to deliver a packed issue on the latest developments in Immunotherapy. The issue covers hot topics such as immunostimulants, Passive Antibody Mediated Immunotherapy, Clinical Applications of A Peptide Based Vaccine, Challenges for Clinical Design of Immunotherapy Trials, The EGFRv3 Peptide Vaccine, Stem Cell Therapy and Dendritic Cell Vaccines, Dendritic Glioma Fusion Vaccine, Adoptive Cellular Immunotherapy, Virus Mediated Immunotherapy, and so much more.
1. Cover - p. 1 2. Contents - p. 2 3. Forthcoming issues - p. 3 4. Preface - p. 4 5. Biologic Principles of Immunotherapy for Malignant Gliomas - p. 5 6. Mechanisms of Local Immunoresistance in Glioma - p. 18 7. Glioblastoma-Derived Mechanisms of Systemic Immunosuppression - p. 29 8. Microglia and Central Nervous System Immunity - p. 38 9. Immunostimulants for Malignant Gliomas - p. 46 10. Passive Antibody-Mediated Immunotherapy for the Treatment of Malignant Gliomas - p. 56 11. Interferon-gamma in Brain Tumor Immunotherapy - p. 63 12. The Epidermal Growth Factor Variant III Peptide Vaccine for Treatment of Malignant Gliomas - p. 68 13. Clinical Applications of a Peptide-Based Vaccine for Glioblastoma - p. 74 14. Heat Shock Proteins in Glioblastomas - p. 86 15. The Role of Tregs in Glioma-Mediated Immunosuppression: Potential Target for Intervention - p. 97 16. Dendritic Cell Vaccines for Brain Tumors - p. 107 17. Glioma Stem Cell Research for the Development of Immunotherapy - p. 118 18. Virally Mediated Immunotherapy for Brain Tumors - p. 125 19. Distinguishing Glioma Recurrence from Treatment Effect After Radiochemotherapy and Immunotherapy - p. 134 20. Immunotherapy Combined with Chemotherapy in the Treatment of Tumors - p. 138 21. Monitoring Immune Responses After Glioma Vaccine Immunotherapy - p. 145 22. Challenges in Clinical Design of Immunotherapy Trials for Malignant Glioma - p. 149 23. Index - p. 160
