Comprehensive and lavishly illustrated, McKee’s Pathology of the Skin, 5th Edition, is your reference of choice for up-to-date, authoritative information on dermatopathology. You’ll find clinical guidance from internationally renowned experts along with details on etiology, pathogenesis, histopathology, and differential diagnosis – making this unique reference unparalleled in its wealth of clinical and histopathological material. The 5th Edition of this classic text is a must-have resource for practicing dermatopathologists and general pathologists who sign out skin biopsies.
1. Introduction - p. 171 2. Pemphigus - p. 171 3. Acantholytic dermatoses with dyskeratosis - p. 188 4. References - p. 200.e1 5. Chapter 6 Spongiotic, psoriasiform and pustular dermatoses - p. 201 6. Eczematous Dermatitis - p. 201 7. Psoriasiform Dermatoses - p. 223 8. Pustular Dermatoses - p. 238 9. References - p. 240.e1 10. Chapter 7 Lichenoid and interface dermatitis - p. 241 11. Lichenoid dermatoses - p. 241 12. Interface dermatoses - p. 261 13. References - p. 282.e1 14. Chapter 8 Superficial and deep perivascular inflammatory dermatoses - p. 283 15. Chapter 9 Granulomatous, necrobiotic and perforating dermatoses - p. 306 16. Sarcoidosis - p. 306 17. Granuloma annulare - p. 313 18. Necrobiosis lipoidica - p. 321 19. Rheumatoid nodule - p. 326 20. Elastolytic granulomata - p. 327 21. Rheumatic fever nodule - p. 332 22. Necrobiotic xanthogranuloma - p. 332 23. Palisaded neutrophilic and granulomatous dermatitis - p. 334 24. ‘Metastatic’ Crohn disease - p. 335 25. Acne agminata - p. 336 26. Periorificial (perioral) dermatitis - p. 337 27. Demodicosis - p. 337 28. Infective granulomata - p. 337 29. Foreign body granulomata - p. 338 30. Granulomatous contact dermatitis - p. 339 31. Granulomata in congenital immunodeficiency syndromes - p. 339 32. Perforating disorders - p. 340 33. Necrotizing infundibular crystalline folliculitis - p. 348 34. Chondrodermatitis nodularis chronica helicis - p. 348 35. References - p. 350.e1 36. Chapter 10 Inflammatory diseases of the subcutaneous fat - p. 351 37. Lipodystrophy - p. 380 38. References - p. 388.e1 39. Chapter 11 Diseases of the oral mucosa - p. 389 40. Hereditary Conditions - p. 391 41. Reactive Conditions - p. 400 42. Ulcerative Conditions - p. 407 43. Papillary Lesions - p. 411 44. Tumorlike Conditions - p. 414 45. Infections - p. 429 46. Lichenoid and Hypersensitivity Reactions - p. 432 47. Autoimmune Conditions - p. 439 48. Salivary Gland Disease - p. 442 49. Premalignant Conditions - p. 451 50. Squamous Cell Carcinoma and Variants - p. 456 51. Oral Lymphoma - p. 463 52. Pigmented Lesions - p. 463 53. Other Tumors - p. 467 54. References - p. 469.e1 55. Chapter 12 Diseases of the anogenital skin - p. 470 56. Introduction - p. 470 57. Normal female anatomy - p. 471 58. Normal male anatomy - p. 472 59. Embryology - p. 472 60. Pubic hair - p. 474 61. Anogenital mammary-like glands - p. 474 62. Normal variants - p. 476 63. Inflammatory dermatoses - p. 477 64. Associations with systemic disease - p. 494 65. Infectious diseases - p. 495 66. Miscellaneous conditions - p. 514 67. Genital pigmentation - p. 516 68. Benign epithelial lesions - p. 520 69. Genital intraepithelial neoplasia and squamous cell carcinoma - p. 524 70. Cloacogenic carcinoma - p. 546 71. Tumors of anogenital mammary-like glands - p. 546 72. Other vulval adnexal neoplasms - p. 550 73. Basal cell carcinoma - p. 550 74. Metastatic tumors - p. 551 75. Lymphoma and leukemia - p. 551 76. Juvenile xanthogranuloma - p. 551 77. Langerhans cell histiocytosis - p. 552 78. Soft tissue tumors - p. 552 79. References - p. 558.e1 80. Chapter 13 Degenerative and metabolic diseases - p. 559 81. The hyperlipidemias - p. 559 82. Angiokeratoma corporis diffusum - p. 569 83. The amyloidoses - p. 572 84. Colloid milium - p. 582 85. Hyalinosis cutis et mucosae - p. 585 86. Cutaneous macroglobulinosis - p. 588 87. Porphyria - p. 589 88. Pseudoporphyria - p. 599 89. Gout - p. 601 90. Ochronosis - p. 603 91. Hartnup disease - p. 606 92. Pellagra - p. 606 93. Scurvy - p. 607 94. Calcinosis cutis - p. 607 95. The mucinoses - p. 612 96. Acanthosis nigricans - p. 626 97. Acrodermatitis enteropathica - p. 628 98. Necrolytic migratory erythema - p. 630 99. Bullosis diabeticorum - p. 631 100. References - p. 632.e1 101. Chapter 14 Cutaneous adverse reactions to drugs - p. 633 102. Adverse Drug Reactions – Introduction - p. 633 103. Adverse Drug Reactions – Clinical Manifestations - p. 635 104. References - p. 681.e1 105. Chapter 15 Neutrophilic and eosinophilic dermatoses - p. 682 106. Pyoderma gangrenosum - p. 682 107. Acute febrile neutrophilic dermatosis (Sweet syndrome) - p. 687 108. Neutrophilic dermatoses associated with gastrointestinal and hepatobiliary disease - p. 690 109. Rheumatoid neutrophilic dermatitis - p. 691 110. Arthropod and arachnid bite reactions - p. 693 111. Seabather's eruption and coelenterate stings - p. 695 112. Erythema marginatum rheumaticum - p. 696 113. Still disease - p. 696 114. Urticaria - p. 697 115. Papular urticaria - p. 702 116. Neutrophilic urticarial dermatosis - p. 702 117. Cutaneous atypical neutrophilic dermatosis with lipodystrophy and elevated temperature - p. 703 118. Hypereosinophilic syndrome - p. 703 119. Eosinophilic cellulitis - p. 704 120. Eosinophilic pustular folliculitis - p. 706 121. Incontinentia pigmenti - p. 706 122. Toxic erythema of the neonate - p. 709 123. Hidradenitis suppurativa - p. 709 124. Prurigo pigmentosa - p. 712 125. References - p. 713.e1 126. Chapter 16 Vascular diseases - p. 714 127. Introduction - p. 714 128. Leukocytoclastic vasculitis - p. 714 129. IgA vasculitis (Henoch-Schönlein purpura) - p. 721 130. Infantile acute hemorrhagic edema - p. 723 131. Urticarial vasculitis - p. 723 132. Granulomatosis with polyangiitis - p. 724 133. Eosinophilic granulomatosis with polyangiitis - p. 728 134. Microscopic polyangiitis - p. 731 135. Polyarteritis nodosa - p. 732 136. Kawasaki disease (mucocutaneous lymph node syndrome) - p. 737 137. Granuloma faciale - p. 739 138. Erythema elevatum diutinum - p. 741 139. Behçet disease - p. 743 140. Thromboangiitis obliterans - p. 747 141. Giant cell arteritis (temporal arteritis) - p. 747 142. Juvenile temporal arteritis - p. 750 143. Takayasu arteritis - p. 750 144. Infection-related vasculitis - p. 751 145. Paraneoplastic vasculitis - p. 753 146. Vasculitis associated with palisaded neutrophilic and granulomatous dermatitis - p. 754 147. Lymphocytic vasculitis - p. 754 148. Malignant atrophic papulosis - p. 755 149. Livedoid vasculopathy and atrophie blanche - p. 757 150. Dermatological manifestations of cholesterol crystal embolism and embolism from atrial myxoma - p. 759 151. Disseminated intravascular coagulation - p. 760 152. Cryoglobulinemia - p. 762 153. Antiphospholipid antibody syndrome and Sneddon syndrome - p. 764 154. Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome - p. 765 155. Immune thrombocytopenic purpura - p. 766 156. Factor V (Leiden) mutation - p. 767 157. Hypergammaglobulinemic purpura - p. 767 158. Hyperimmunoglobulinemia D syndrome/mevalonate kinase deficiency - p. 768 159. Superficial thrombophlebitis - p. 768 160. Sclerosing lymphangitis - p. 768 161. Senile purpura - p. 769 162. Cocaine-related retiform purpura - p. 769 163. References - p. 770.e1 164. Chapter 17 Idiopathic connective tissue disorders - p. 771 165. Lupus erythematosus - p. 771 166. Systemic sclerosis - p. 797 167. Localized scleroderma (morphea) - p. 807 168. Atrophoderma of Pasini and Pierini - p. 813 169. Eosinophilic fasciitis - p. 814 170. Polymyositis/dermatomyositis - p. 816 171. Mixed connective tissue disease - p. 822 172. Relapsing polychondritis - p. 823 173. References - p. 825.e1 174. Chapter 18 Infectious diseases of the skin - p. 826 175. Viral Infections - p. 827 176. Bacterial Infections - p. 858 177. Protozoal Infections - p. 916 178. Algal Infections - p. 923 179. Fungal Infections - p. 924 180. Diseases Caused by Mesomycetozoea - p. 964 181. Arthropod Infestations - p. 966 182. Nematode Infestation - p. 969 183. Trematode Infestation - p. 973 184. Cestode Infestation - p. 974 185. References - p. 975.e1 186. Chapter 19 Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)-associated cutaneous diseases - p. 976 187. Chapter 20 Disorders of pigmentation - p. 990 188. Disorders of Hypopigmentation - p. 990 189. Disorders of Hyperpigmentation - p. 1002 190. References - p. 1014.e1 191. Chapter 21 Diseases of collagen and elastic tissue - p. 1015 192. Diseases of Collagen: Generalized Disorders - p. 1015 193. Diseases of Collagen: Localized Disorders - p. 1029 194. Diseases of Elastic Tissue - p. 1030 195. References - p. 1050.e1 196. Chapter 22 Diseases of the hair - p. 1051 197. Classification of Alopecia - p. 1065 198. Hair Shaft Diseases - p. 1110 199. Miscellaneous Follicular Dermatoses - p. 1120 200. References - p. 1128.e1 201. Chapter 23 Diseases of the nails - p. 1129 202. Chapter 24 Tumors of the surface epithelium - p. 1156 203. Epidermal nevi - p. 1156 204. Cornu cutaneum - p. 1159 205. Acanthoma fissuratum - p. 1160 206. Seborrheic keratosis - p. 1160 207. Dermatosis papulosa nigra - p. 1163 208. Actinic lentigo - p. 1166 209. Large cell acanthoma - p. 1167 210. Stucco keratoses - p. 1168 211. Intraepidermal epithelioma of Borst-Jadassohn - p. 1168 212. Porokeratoma - p. 1168 213. Psoriasiform keratosis - p. 1169 214. Granular parakeratotic acanthoma - p. 1169 215. Clear cell acanthoma - p. 1169 216. Pseudoepitheliomatous hyperplasia - p. 1170 217. Basal cell carcinoma - p. 1170 218. Nevoid basal cell carcinoma syndrome - p. 1186 219. Bazex-Dupré-Christol and Rombo syndromes - p. 1187 220. Fibroepithelioma of Pinkus - p. 1188 221. Actinic keratoses - p. 1189 222. Squamous carcinoma in situ (Bowen disease) - p. 1192 223. PUVA keratosis - p. 1197 224. Arsenical keratoses - p. 1198 225. Squamous cell carcinoma - p. 1198 226. Variants of squamous cell carcinoma - p. 1207 227. Metaplastic carcinoma of the skin (carcinosarcoma, carcinoma with heterologous differentiation) - p. 1222 228. Squamous cell carcinoma with chronic lymphocytic leukemia - p. 1223 229. Xeroderma pigmentosum - p. 1223 230. Merkel cell carcinoma - p. 1225 231. Lymphoepithelioma-like carcinoma of the skin - p. 1231 232. References - p. 1233.e1 233. Chapter 25 Melanocytic nevi - p. 1234 234. Ephelide - p. 1234 235. Lentigo simplex - p. 1234 236. Labial melanotic macule and labial lentigo - p. 1235 237. Laugier-Hunziker syndrome - p. 1235 238. Oral melanoacanthoma - p. 1236 239. Cutaneous melanoacanthoma - p. 1236 240. Peutz-Jeghers syndrome - p. 1236 241. Genital lentiginosis - p. 1236 242. Acral lentigo - p. 1236 243. Multiple lentigines syndrome - p. 1236 244. Carney complex - p. 1237 245. Centrofacial lentiginosis - p. 1237 246. PUVA and sunbed lentigines - p. 1238 247. Ink spot lentigo - p. 1238 248. Becker nevus - p. 1238 249. Pseudomelanocytic nests - p. 1240 250. Melanocytic nevus - p. 1240 251. Clonal nevus - p. 1250 252. Eccrine centered nevus - p. 1250 253. Melanocytic nevi at special sites - p. 1250 254. Acral nevus - p. 1254 255. Nevus spilus - p. 1256 256. Cockarde nevus - p. 1256 257. Combined nevus (melanocytic nevus with phenotypic heterogeneity) - p. 1257 258. Recurrent and sclerosing nevus - p. 1257 259. Balloon cell nevus - p. 1259 260. Halo nevus - p. 1259 261. Meyerson nevus - p. 1262 262. Spitz nevus, atypical Spitz nevus and spitzoid melanoma - p. 1263 263. Pigmented epithelioid cell nevus - p. 1270 264. Pagetoid Spitz nevus - p. 1270 265. Desmoplastic nevus - p. 1271 266. Pigmented spindle cell tumor of Reed - p. 1273 267. Deep penetrating nevus - p. 1275 268. Dysplastic nevus syndrome and dysplastic nevi - p. 1280 269. Atypical (dysplastic) lentiginous nevus of the elderly - p. 1287 270. Congenital nevus - p. 1287 271. Congenital nevi in neonates and young children - p. 1289 272. Dermal melanocytic lesions (dermal melanocytoses) - p. 1292 273. Superficial atypical melanocytic proliferations of unknown significance - p. 1303 274. Melanocytic tumors of uncertain malignant potential - p. 1304 275. The molecular pathology of melanocytic nevi - p. 1304 276. References - p. 1309.e1 277. Chapter 26 Melanoma - p. 1310 278. Melanoma - p. 1310 279. References - p. 1362.e1 280. Chapter 27 Tumors of the conjunctiva - p. 1363 281. Chapter 28 Sentinel lymph node biopsies - p. 1388 282. Chapter 29 Cutaneous lymphoproliferative diseases and related disorders - p. 1403 283. T-Cell Lymphomas - p. 1405 284. Benign Cutaneous Infiltrates That Can Be Mistaken for Cutaneous T-Cell Lymphoma (Cutaneous T-Cell Pseudolymphoma) - p. 1455 285. B-Cell Lymphomas - p. 1460 286. Benign Cutaneous Infiltrates That Can Be Mistaken for Cutaneous B-Cell Lymphoma (So-Called Cutaneous B-Cell Pseudolymphoma) - p. 1482 287. Histiocytic Disorders - p. 1488 288. Cutaneous and Mucocutaneous Histiocytoses - p. 1497 289. Cutaneous Leukemic Infiltrates and Precursor Cell Neoplasms - p. 1512 290. References - p. 1519.e1 291. Chapter 30 Cutaneous metastases and Paget disease of the skin - p. 1520 292. Chapter 31 Tumors of the hair follicle - p. 1545 293. Hair nevi - p. 1545 294. Hair follicle nevus - p. 1545 295. Woolly hair nevus - p. 1545 296. Comedo nevus - p. 1545 297. Basaloid follicular hamartoma - p. 1546 298. Dilated pore - p. 1548 299. Pilar sheath acanthoma - p. 1549 300. Follicular infundibulum tumor (infundibuloma) - p. 1550 301. Trichoadenoma - p. 1550 302. Trichilemmoma and Cowden disease - p. 1551 303. Desmoplastic trichilemmoma - p. 1554 304. Trichilemmal carcinoma - p. 1554 305. Proliferating trichilemmal (pilar) cyst - p. 1557 306. Pilomatrixoma - p. 1560 307. Pilomatrix carcinoma - p. 1563 308. Melanocytic matricoma - p. 1564 309. Trichofolliculoma - p. 1566 310. Folliculosebaceous cystic hamartoma - p. 1567 311. Sebaceous trichofolliculoma - p. 1569 312. Trichoepithelioma - p. 1570 313. Desmoplastic trichoepithelioma (sclerosing epithelial hamartoma) - p. 1574 314. Trichoblastoma - p. 1576 315. Malignant trichoblastoma - p. 1580 316. Cutaneous lymphadenoma (lymphoepithelial tumor of the skin) - p. 1583 317. Perifollicular fibroma - p. 1584 318. Fibrofolliculoma - p. 1585 319. Trichodiscoma, Birt-Hogg-Dubé, and Hornstein-Knickenberg syndromes - p. 1586 320. Neurofollicular hamartoma (spindle cell predominant trichodiscoma) - p. 1588 321. References - p. 1588.e1 322. Chapter 32 Tumors and related lesions of the sebaceous glands - p. 1589 323. Chapter 33 Tumors of the sweat glands - p. 1611 324. Apocrine nevus - p. 1611 325. Apocrine hidrocystoma and apocrine cystadenoma - p. 1611 326. Hybrid epidermoid and apocrine cyst - p. 1612 327. Syringocystadenoma papilliferum - p. 1612 328. Syringocystadenocarcinoma papilliferum - p. 1615 329. Hidradenoma papilliferum - p. 1615 330. Tubular apocrine adenoma - p. 1616 331. Adenoma and adenocarcinoma of the anogenital mammary-like glands - p. 1617 332. Nipple adenoma - p. 1617 333. Syringomatous adenoma of the nipple - p. 1618 334. Apocrine poroma - p. 1618 335. Cutaneous oncocytoma - p. 1619 336. Apocrine carcinoma - p. 1619 337. Primary cutaneous cribriform apocrine carcinoma - p. 1621 338. Ceruminous gland tumors - p. 1623 339. Mixed tumor of the skin - p. 1623 340. Malignant mixed tumor - p. 1628 341. Myoepithelioma and malignant myoepithelioma - p. 1630 342. Eccrine nevus - p. 1632 343. Adnexal polyp of neonatal skin - p. 1632 344. Eccrine syringofibroadenoma - p. 1632 345. Eccrine angiomatous hamartoma - p. 1633 346. Porokeratotic eccrine ostial and dermal duct nevus - p. 1634 347. Eccrine hidrocystoma - p. 1635 348. Hidroacanthoma simplex - p. 1637 349. Eccrine poroma - p. 1638 350. Dermal duct tumor - p. 1639 351. Eccrine porocarcinoma - p. 1641 352. Syringoma - p. 1644 353. Papillary eccrine adenoma - p. 1646 354. Digital papillary adenocarcinoma - p. 1648 355. Hidradenoma - p. 1650 356. Clear cell hidradenocarcinoma - p. 1654 357. Dermal cylindroma - p. 1657 358. Malignant cylindroma - p. 1659 359. Eccrine spiradenoma - p. 1659 360. Eccrine spiradenocarcinoma - p. 1662 361. Syringoid eccrine carcinoma - p. 1665 362. Microcystic adnexal carcinoma - p. 1667 363. Primary cutaneous adenoid cystic carcinoma - p. 1670 364. Primary cutaneous mucinous carcinoma - p. 1672 365. Endocrine mucin-producing sweat gland carcinoma - p. 1675 366. Mammary-type secretory carcinoma of the skin - p. 1676 367. Eccrine ductal carcinoma - p. 1676 368. Squamoid eccrine ductal carcinoma - p. 1678 369. Polymorphous sweat gland carcinoma - p. 1678 370. Primary cutaneous signet ring cell carcinoma - p. 1679 371. References - p. 1679.e1 372. Chapter 34 Cutaneous cysts - p. 1680 373. Chapter 35 Connective tissue tumors - p. 1698 374. Adipocytic Tumors - p. 1700 375. Tumors of Fibrous, Fibroblastic and Myofibroblastic Tissue - p. 1714 376. Fibrohistiocytic tumors - p. 1757 377. Nerve Sheath and Neuroectodermal Tumors and Tumorlike Lesions - p. 1781 378. Smooth Muscle Tumors - p. 1813 379. Striated Muscle Tumors - p. 1818 380. Tumors of Vascular Origin - p. 1822 381. Tumors of Bone and Cartilage-Forming Tissue - p. 1874 382. Miscellaneous Reactive, Benign Lesions and Tumors of Uncertain Differentiation - p. 1878 383. Miscellaneous Low-Grade and Malignant Tumors - p. 1885 384. References - p. 1894.e1 385. Chapter 36 Animal models of skin disease - p. 1895 386. Index - p. I-1 387. Glossary of abbreviations - p. xii
Comprehensive and lavishly illustrated, McKee’s Pathology of the Skin, 5th Edition, is your reference of choice for up-to-date, authoritative information on dermatopathology. You’ll find clinical guidance from internationally renowned experts along with details on etiology, pathogenesis, histopathology, and differential diagnosis – making this unique reference unparalleled in its wealth of clinical and histopathological material. The 5th Edition of this classic text is a must-have resource for practicing dermatopathologists and general pathologists who sign out skin biopsies.
1. Introduction - p. 171 2. Pemphigus - p. 171 3. Acantholytic dermatoses with dyskeratosis - p. 188 4. References - p. 200.e1 5. Chapter 6 Spongiotic, psoriasiform and pustular dermatoses - p. 201 6. Eczematous Dermatitis - p. 201 7. Psoriasiform Dermatoses - p. 223 8. Pustular Dermatoses - p. 238 9. References - p. 240.e1 10. Chapter 7 Lichenoid and interface dermatitis - p. 241 11. Lichenoid dermatoses - p. 241 12. Interface dermatoses - p. 261 13. References - p. 282.e1 14. Chapter 8 Superficial and deep perivascular inflammatory dermatoses - p. 283 15. Chapter 9 Granulomatous, necrobiotic and perforating dermatoses - p. 306 16. Sarcoidosis - p. 306 17. Granuloma annulare - p. 313 18. Necrobiosis lipoidica - p. 321 19. Rheumatoid nodule - p. 326 20. Elastolytic granulomata - p. 327 21. Rheumatic fever nodule - p. 332 22. Necrobiotic xanthogranuloma - p. 332 23. Palisaded neutrophilic and granulomatous dermatitis - p. 334 24. ‘Metastatic’ Crohn disease - p. 335 25. Acne agminata - p. 336 26. Periorificial (perioral) dermatitis - p. 337 27. Demodicosis - p. 337 28. Infective granulomata - p. 337 29. Foreign body granulomata - p. 338 30. Granulomatous contact dermatitis - p. 339 31. Granulomata in congenital immunodeficiency syndromes - p. 339 32. Perforating disorders - p. 340 33. Necrotizing infundibular crystalline folliculitis - p. 348 34. Chondrodermatitis nodularis chronica helicis - p. 348 35. References - p. 350.e1 36. Chapter 10 Inflammatory diseases of the subcutaneous fat - p. 351 37. Lipodystrophy - p. 380 38. References - p. 388.e1 39. Chapter 11 Diseases of the oral mucosa - p. 389 40. Hereditary Conditions - p. 391 41. Reactive Conditions - p. 400 42. Ulcerative Conditions - p. 407 43. Papillary Lesions - p. 411 44. Tumorlike Conditions - p. 414 45. Infections - p. 429 46. Lichenoid and Hypersensitivity Reactions - p. 432 47. Autoimmune Conditions - p. 439 48. Salivary Gland Disease - p. 442 49. Premalignant Conditions - p. 451 50. Squamous Cell Carcinoma and Variants - p. 456 51. Oral Lymphoma - p. 463 52. Pigmented Lesions - p. 463 53. Other Tumors - p. 467 54. References - p. 469.e1 55. Chapter 12 Diseases of the anogenital skin - p. 470 56. Introduction - p. 470 57. Normal female anatomy - p. 471 58. Normal male anatomy - p. 472 59. Embryology - p. 472 60. Pubic hair - p. 474 61. Anogenital mammary-like glands - p. 474 62. Normal variants - p. 476 63. Inflammatory dermatoses - p. 477 64. Associations with systemic disease - p. 494 65. Infectious diseases - p. 495 66. Miscellaneous conditions - p. 514 67. Genital pigmentation - p. 516 68. Benign epithelial lesions - p. 520 69. Genital intraepithelial neoplasia and squamous cell carcinoma - p. 524 70. Cloacogenic carcinoma - p. 546 71. Tumors of anogenital mammary-like glands - p. 546 72. Other vulval adnexal neoplasms - p. 550 73. Basal cell carcinoma - p. 550 74. Metastatic tumors - p. 551 75. Lymphoma and leukemia - p. 551 76. Juvenile xanthogranuloma - p. 551 77. Langerhans cell histiocytosis - p. 552 78. Soft tissue tumors - p. 552 79. References - p. 558.e1 80. Chapter 13 Degenerative and metabolic diseases - p. 559 81. The hyperlipidemias - p. 559 82. Angiokeratoma corporis diffusum - p. 569 83. The amyloidoses - p. 572 84. Colloid milium - p. 582 85. Hyalinosis cutis et mucosae - p. 585 86. Cutaneous macroglobulinosis - p. 588 87. Porphyria - p. 589 88. Pseudoporphyria - p. 599 89. Gout - p. 601 90. Ochronosis - p. 603 91. Hartnup disease - p. 606 92. Pellagra - p. 606 93. Scurvy - p. 607 94. Calcinosis cutis - p. 607 95. The mucinoses - p. 612 96. Acanthosis nigricans - p. 626 97. Acrodermatitis enteropathica - p. 628 98. Necrolytic migratory erythema - p. 630 99. Bullosis diabeticorum - p. 631 100. References - p. 632.e1 101. Chapter 14 Cutaneous adverse reactions to drugs - p. 633 102. Adverse Drug Reactions – Introduction - p. 633 103. Adverse Drug Reactions – Clinical Manifestations - p. 635 104. References - p. 681.e1 105. Chapter 15 Neutrophilic and eosinophilic dermatoses - p. 682 106. Pyoderma gangrenosum - p. 682 107. Acute febrile neutrophilic dermatosis (Sweet syndrome) - p. 687 108. Neutrophilic dermatoses associated with gastrointestinal and hepatobiliary disease - p. 690 109. Rheumatoid neutrophilic dermatitis - p. 691 110. Arthropod and arachnid bite reactions - p. 693 111. Seabather's eruption and coelenterate stings - p. 695 112. Erythema marginatum rheumaticum - p. 696 113. Still disease - p. 696 114. Urticaria - p. 697 115. Papular urticaria - p. 702 116. Neutrophilic urticarial dermatosis - p. 702 117. Cutaneous atypical neutrophilic dermatosis with lipodystrophy and elevated temperature - p. 703 118. Hypereosinophilic syndrome - p. 703 119. Eosinophilic cellulitis - p. 704 120. Eosinophilic pustular folliculitis - p. 706 121. Incontinentia pigmenti - p. 706 122. Toxic erythema of the neonate - p. 709 123. Hidradenitis suppurativa - p. 709 124. Prurigo pigmentosa - p. 712 125. References - p. 713.e1 126. Chapter 16 Vascular diseases - p. 714 127. Introduction - p. 714 128. Leukocytoclastic vasculitis - p. 714 129. IgA vasculitis (Henoch-Schönlein purpura) - p. 721 130. Infantile acute hemorrhagic edema - p. 723 131. Urticarial vasculitis - p. 723 132. Granulomatosis with polyangiitis - p. 724 133. Eosinophilic granulomatosis with polyangiitis - p. 728 134. Microscopic polyangiitis - p. 731 135. Polyarteritis nodosa - p. 732 136. Kawasaki disease (mucocutaneous lymph node syndrome) - p. 737 137. Granuloma faciale - p. 739 138. Erythema elevatum diutinum - p. 741 139. Behçet disease - p. 743 140. Thromboangiitis obliterans - p. 747 141. Giant cell arteritis (temporal arteritis) - p. 747 142. Juvenile temporal arteritis - p. 750 143. Takayasu arteritis - p. 750 144. Infection-related vasculitis - p. 751 145. Paraneoplastic vasculitis - p. 753 146. Vasculitis associated with palisaded neutrophilic and granulomatous dermatitis - p. 754 147. Lymphocytic vasculitis - p. 754 148. Malignant atrophic papulosis - p. 755 149. Livedoid vasculopathy and atrophie blanche - p. 757 150. Dermatological manifestations of cholesterol crystal embolism and embolism from atrial myxoma - p. 759 151. Disseminated intravascular coagulation - p. 760 152. Cryoglobulinemia - p. 762 153. Antiphospholipid antibody syndrome and Sneddon syndrome - p. 764 154. Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome - p. 765 155. Immune thrombocytopenic purpura - p. 766 156. Factor V (Leiden) mutation - p. 767 157. Hypergammaglobulinemic purpura - p. 767 158. Hyperimmunoglobulinemia D syndrome/mevalonate kinase deficiency - p. 768 159. Superficial thrombophlebitis - p. 768 160. Sclerosing lymphangitis - p. 768 161. Senile purpura - p. 769 162. Cocaine-related retiform purpura - p. 769 163. References - p. 770.e1 164. Chapter 17 Idiopathic connective tissue disorders - p. 771 165. Lupus erythematosus - p. 771 166. Systemic sclerosis - p. 797 167. Localized scleroderma (morphea) - p. 807 168. Atrophoderma of Pasini and Pierini - p. 813 169. Eosinophilic fasciitis - p. 814 170. Polymyositis/dermatomyositis - p. 816 171. Mixed connective tissue disease - p. 822 172. Relapsing polychondritis - p. 823 173. References - p. 825.e1 174. Chapter 18 Infectious diseases of the skin - p. 826 175. Viral Infections - p. 827 176. Bacterial Infections - p. 858 177. Protozoal Infections - p. 916 178. Algal Infections - p. 923 179. Fungal Infections - p. 924 180. Diseases Caused by Mesomycetozoea - p. 964 181. Arthropod Infestations - p. 966 182. Nematode Infestation - p. 969 183. Trematode Infestation - p. 973 184. Cestode Infestation - p. 974 185. References - p. 975.e1 186. Chapter 19 Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)-associated cutaneous diseases - p. 976 187. Chapter 20 Disorders of pigmentation - p. 990 188. Disorders of Hypopigmentation - p. 990 189. Disorders of Hyperpigmentation - p. 1002 190. References - p. 1014.e1 191. Chapter 21 Diseases of collagen and elastic tissue - p. 1015 192. Diseases of Collagen: Generalized Disorders - p. 1015 193. Diseases of Collagen: Localized Disorders - p. 1029 194. Diseases of Elastic Tissue - p. 1030 195. References - p. 1050.e1 196. Chapter 22 Diseases of the hair - p. 1051 197. Classification of Alopecia - p. 1065 198. Hair Shaft Diseases - p. 1110 199. Miscellaneous Follicular Dermatoses - p. 1120 200. References - p. 1128.e1 201. Chapter 23 Diseases of the nails - p. 1129 202. Chapter 24 Tumors of the surface epithelium - p. 1156 203. Epidermal nevi - p. 1156 204. Cornu cutaneum - p. 1159 205. Acanthoma fissuratum - p. 1160 206. Seborrheic keratosis - p. 1160 207. Dermatosis papulosa nigra - p. 1163 208. Actinic lentigo - p. 1166 209. Large cell acanthoma - p. 1167 210. Stucco keratoses - p. 1168 211. Intraepidermal epithelioma of Borst-Jadassohn - p. 1168 212. Porokeratoma - p. 1168 213. Psoriasiform keratosis - p. 1169 214. Granular parakeratotic acanthoma - p. 1169 215. Clear cell acanthoma - p. 1169 216. Pseudoepitheliomatous hyperplasia - p. 1170 217. Basal cell carcinoma - p. 1170 218. Nevoid basal cell carcinoma syndrome - p. 1186 219. Bazex-Dupré-Christol and Rombo syndromes - p. 1187 220. Fibroepithelioma of Pinkus - p. 1188 221. Actinic keratoses - p. 1189 222. Squamous carcinoma in situ (Bowen disease) - p. 1192 223. PUVA keratosis - p. 1197 224. Arsenical keratoses - p. 1198 225. Squamous cell carcinoma - p. 1198 226. Variants of squamous cell carcinoma - p. 1207 227. Metaplastic carcinoma of the skin (carcinosarcoma, carcinoma with heterologous differentiation) - p. 1222 228. Squamous cell carcinoma with chronic lymphocytic leukemia - p. 1223 229. Xeroderma pigmentosum - p. 1223 230. Merkel cell carcinoma - p. 1225 231. Lymphoepithelioma-like carcinoma of the skin - p. 1231 232. References - p. 1233.e1 233. Chapter 25 Melanocytic nevi - p. 1234 234. Ephelide - p. 1234 235. Lentigo simplex - p. 1234 236. Labial melanotic macule and labial lentigo - p. 1235 237. Laugier-Hunziker syndrome - p. 1235 238. Oral melanoacanthoma - p. 1236 239. Cutaneous melanoacanthoma - p. 1236 240. Peutz-Jeghers syndrome - p. 1236 241. Genital lentiginosis - p. 1236 242. Acral lentigo - p. 1236 243. Multiple lentigines syndrome - p. 1236 244. Carney complex - p. 1237 245. Centrofacial lentiginosis - p. 1237 246. PUVA and sunbed lentigines - p. 1238 247. Ink spot lentigo - p. 1238 248. Becker nevus - p. 1238 249. Pseudomelanocytic nests - p. 1240 250. Melanocytic nevus - p. 1240 251. Clonal nevus - p. 1250 252. Eccrine centered nevus - p. 1250 253. Melanocytic nevi at special sites - p. 1250 254. Acral nevus - p. 1254 255. Nevus spilus - p. 1256 256. Cockarde nevus - p. 1256 257. Combined nevus (melanocytic nevus with phenotypic heterogeneity) - p. 1257 258. Recurrent and sclerosing nevus - p. 1257 259. Balloon cell nevus - p. 1259 260. Halo nevus - p. 1259 261. Meyerson nevus - p. 1262 262. Spitz nevus, atypical Spitz nevus and spitzoid melanoma - p. 1263 263. Pigmented epithelioid cell nevus - p. 1270 264. Pagetoid Spitz nevus - p. 1270 265. Desmoplastic nevus - p. 1271 266. Pigmented spindle cell tumor of Reed - p. 1273 267. Deep penetrating nevus - p. 1275 268. Dysplastic nevus syndrome and dysplastic nevi - p. 1280 269. Atypical (dysplastic) lentiginous nevus of the elderly - p. 1287 270. Congenital nevus - p. 1287 271. Congenital nevi in neonates and young children - p. 1289 272. Dermal melanocytic lesions (dermal melanocytoses) - p. 1292 273. Superficial atypical melanocytic proliferations of unknown significance - p. 1303 274. Melanocytic tumors of uncertain malignant potential - p. 1304 275. The molecular pathology of melanocytic nevi - p. 1304 276. References - p. 1309.e1 277. Chapter 26 Melanoma - p. 1310 278. Melanoma - p. 1310 279. References - p. 1362.e1 280. Chapter 27 Tumors of the conjunctiva - p. 1363 281. Chapter 28 Sentinel lymph node biopsies - p. 1388 282. Chapter 29 Cutaneous lymphoproliferative diseases and related disorders - p. 1403 283. T-Cell Lymphomas - p. 1405 284. Benign Cutaneous Infiltrates That Can Be Mistaken for Cutaneous T-Cell Lymphoma (Cutaneous T-Cell Pseudolymphoma) - p. 1455 285. B-Cell Lymphomas - p. 1460 286. Benign Cutaneous Infiltrates That Can Be Mistaken for Cutaneous B-Cell Lymphoma (So-Called Cutaneous B-Cell Pseudolymphoma) - p. 1482 287. Histiocytic Disorders - p. 1488 288. Cutaneous and Mucocutaneous Histiocytoses - p. 1497 289. Cutaneous Leukemic Infiltrates and Precursor Cell Neoplasms - p. 1512 290. References - p. 1519.e1 291. Chapter 30 Cutaneous metastases and Paget disease of the skin - p. 1520 292. Chapter 31 Tumors of the hair follicle - p. 1545 293. Hair nevi - p. 1545 294. Hair follicle nevus - p. 1545 295. Woolly hair nevus - p. 1545 296. Comedo nevus - p. 1545 297. Basaloid follicular hamartoma - p. 1546 298. Dilated pore - p. 1548 299. Pilar sheath acanthoma - p. 1549 300. Follicular infundibulum tumor (infundibuloma) - p. 1550 301. Trichoadenoma - p. 1550 302. Trichilemmoma and Cowden disease - p. 1551 303. Desmoplastic trichilemmoma - p. 1554 304. Trichilemmal carcinoma - p. 1554 305. Proliferating trichilemmal (pilar) cyst - p. 1557 306. Pilomatrixoma - p. 1560 307. Pilomatrix carcinoma - p. 1563 308. Melanocytic matricoma - p. 1564 309. Trichofolliculoma - p. 1566 310. Folliculosebaceous cystic hamartoma - p. 1567 311. Sebaceous trichofolliculoma - p. 1569 312. Trichoepithelioma - p. 1570 313. Desmoplastic trichoepithelioma (sclerosing epithelial hamartoma) - p. 1574 314. Trichoblastoma - p. 1576 315. Malignant trichoblastoma - p. 1580 316. Cutaneous lymphadenoma (lymphoepithelial tumor of the skin) - p. 1583 317. Perifollicular fibroma - p. 1584 318. Fibrofolliculoma - p. 1585 319. Trichodiscoma, Birt-Hogg-Dubé, and Hornstein-Knickenberg syndromes - p. 1586 320. Neurofollicular hamartoma (spindle cell predominant trichodiscoma) - p. 1588 321. References - p. 1588.e1 322. Chapter 32 Tumors and related lesions of the sebaceous glands - p. 1589 323. Chapter 33 Tumors of the sweat glands - p. 1611 324. Apocrine nevus - p. 1611 325. Apocrine hidrocystoma and apocrine cystadenoma - p. 1611 326. Hybrid epidermoid and apocrine cyst - p. 1612 327. Syringocystadenoma papilliferum - p. 1612 328. Syringocystadenocarcinoma papilliferum - p. 1615 329. Hidradenoma papilliferum - p. 1615 330. Tubular apocrine adenoma - p. 1616 331. Adenoma and adenocarcinoma of the anogenital mammary-like glands - p. 1617 332. Nipple adenoma - p. 1617 333. Syringomatous adenoma of the nipple - p. 1618 334. Apocrine poroma - p. 1618 335. Cutaneous oncocytoma - p. 1619 336. Apocrine carcinoma - p. 1619 337. Primary cutaneous cribriform apocrine carcinoma - p. 1621 338. Ceruminous gland tumors - p. 1623 339. Mixed tumor of the skin - p. 1623 340. Malignant mixed tumor - p. 1628 341. Myoepithelioma and malignant myoepithelioma - p. 1630 342. Eccrine nevus - p. 1632 343. Adnexal polyp of neonatal skin - p. 1632 344. Eccrine syringofibroadenoma - p. 1632 345. Eccrine angiomatous hamartoma - p. 1633 346. Porokeratotic eccrine ostial and dermal duct nevus - p. 1634 347. Eccrine hidrocystoma - p. 1635 348. Hidroacanthoma simplex - p. 1637 349. Eccrine poroma - p. 1638 350. Dermal duct tumor - p. 1639 351. Eccrine porocarcinoma - p. 1641 352. Syringoma - p. 1644 353. Papillary eccrine adenoma - p. 1646 354. Digital papillary adenocarcinoma - p. 1648 355. Hidradenoma - p. 1650 356. Clear cell hidradenocarcinoma - p. 1654 357. Dermal cylindroma - p. 1657 358. Malignant cylindroma - p. 1659 359. Eccrine spiradenoma - p. 1659 360. Eccrine spiradenocarcinoma - p. 1662 361. Syringoid eccrine carcinoma - p. 1665 362. Microcystic adnexal carcinoma - p. 1667 363. Primary cutaneous adenoid cystic carcinoma - p. 1670 364. Primary cutaneous mucinous carcinoma - p. 1672 365. Endocrine mucin-producing sweat gland carcinoma - p. 1675 366. Mammary-type secretory carcinoma of the skin - p. 1676 367. Eccrine ductal carcinoma - p. 1676 368. Squamoid eccrine ductal carcinoma - p. 1678 369. Polymorphous sweat gland carcinoma - p. 1678 370. Primary cutaneous signet ring cell carcinoma - p. 1679 371. References - p. 1679.e1 372. Chapter 34 Cutaneous cysts - p. 1680 373. Chapter 35 Connective tissue tumors - p. 1698 374. Adipocytic Tumors - p. 1700 375. Tumors of Fibrous, Fibroblastic and Myofibroblastic Tissue - p. 1714 376. Fibrohistiocytic tumors - p. 1757 377. Nerve Sheath and Neuroectodermal Tumors and Tumorlike Lesions - p. 1781 378. Smooth Muscle Tumors - p. 1813 379. Striated Muscle Tumors - p. 1818 380. Tumors of Vascular Origin - p. 1822 381. Tumors of Bone and Cartilage-Forming Tissue - p. 1874 382. Miscellaneous Reactive, Benign Lesions and Tumors of Uncertain Differentiation - p. 1878 383. Miscellaneous Low-Grade and Malignant Tumors - p. 1885 384. References - p. 1894.e1 385. Chapter 36 Animal models of skin disease - p. 1895 386. Index - p. I-1 387. Glossary of abbreviations - p. xii
