Multifaceted Role of IL-1 in Cancer and Inflammation summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. The book presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment and covers topics on the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors.
This is a valuable source for cancer researchers, clinicians and other members of the biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies.
1. Multifaceted Role of IL-1 in Cancer and Inflammation - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. List of contributors - p. Page iv 7. Preface - p. Page vi 8. List of Illustrations - p. Page vii 9. List of Tables - p. Page viii 10. Chapter 1 : Role of IL-1 gene polymorphisms in common solid cancers - p. Page viii 11. Chapter 2 : The role of IL-1 in tumor growth and angiogenesis - p. Page 56 12. Chapter 3 : Interleukin-1-mediated immune suppression and resistance to immunotherapy in cancer - p. Page 80 13. Chapter 4 : Strategies to overcome interleukin-1-mediated immune suppression and resistance to immunotherapy in cancer - p. Page 94 14. Chapter 5 : Modulation of IL-1-mediated inflammation in cancer using a food-based approach: a preventive strategy - p. Page 119 15. Chapter 6 : IL-1-mediated inflammation in COVID-19 - p. Page 136 16. Chapter 7 : Role of IL-1 in bacterial infections - p. Page 155 17. Index - p. Page 171
Multifaceted Role of IL-1 in Cancer and Inflammation summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. The book presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment and covers topics on the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors.
This is a valuable source for cancer researchers, clinicians and other members of the biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies.
1. Multifaceted Role of IL-1 in Cancer and Inflammation - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. List of contributors - p. Page iv 7. Preface - p. Page vi 8. List of Illustrations - p. Page vii 9. List of Tables - p. Page viii 10. Chapter 1 : Role of IL-1 gene polymorphisms in common solid cancers - p. Page viii 11. Chapter 2 : The role of IL-1 in tumor growth and angiogenesis - p. Page 56 12. Chapter 3 : Interleukin-1-mediated immune suppression and resistance to immunotherapy in cancer - p. Page 80 13. Chapter 4 : Strategies to overcome interleukin-1-mediated immune suppression and resistance to immunotherapy in cancer - p. Page 94 14. Chapter 5 : Modulation of IL-1-mediated inflammation in cancer using a food-based approach: a preventive strategy - p. Page 119 15. Chapter 6 : IL-1-mediated inflammation in COVID-19 - p. Page 136 16. Chapter 7 : Role of IL-1 in bacterial infections - p. Page 155 17. Index - p. Page 171