Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA.
The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications.
1. Navigating Non-coding RNA - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. List of contributors - p. Page iv 7. List of Illustrations - p. Page vi 8. List of Tables - p. Page vii 9. Chapter 1 : History and definitions of ncRNAs - p. Page vii 10. Chapter 2 : Regulatory non-coding RNAs-biogenesis, mechanisms of action and role in gene expression regulation - p. Page 29 11. Chapter 3 : Non-coding RNAs: Mechanisms of action - p. Page 72 12. Chapter 4 : Functional characterization of lncRNAs - p. Page 122 13. Chapter 5 : Secondary structural characterization of non-coding RNAs - p. Page 167 14. Chapter 6 : Regulation of non-coding RNAs - p. Page 202 15. Chapter 7 : Non-coding RNAs in human non-infectious diseases - p. Page 245 16. Chapter 8 : Non-coding RNAs in human infectious diseases - p. Page 304 17. Chapter 9 : Therapeutic targeting non-coding RNAs - p. Page 340 18. Index - p. Page 385
Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA.
The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications.
1. Navigating Non-coding RNA - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. List of contributors - p. Page iv 7. List of Illustrations - p. Page vi 8. List of Tables - p. Page vii 9. Chapter 1 : History and definitions of ncRNAs - p. Page vii 10. Chapter 2 : Regulatory non-coding RNAs-biogenesis, mechanisms of action and role in gene expression regulation - p. Page 29 11. Chapter 3 : Non-coding RNAs: Mechanisms of action - p. Page 72 12. Chapter 4 : Functional characterization of lncRNAs - p. Page 122 13. Chapter 5 : Secondary structural characterization of non-coding RNAs - p. Page 167 14. Chapter 6 : Regulation of non-coding RNAs - p. Page 202 15. Chapter 7 : Non-coding RNAs in human non-infectious diseases - p. Page 245 16. Chapter 8 : Non-coding RNAs in human infectious diseases - p. Page 304 17. Chapter 9 : Therapeutic targeting non-coding RNAs - p. Page 340 18. Index - p. Page 385
