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Neurotoxicity of Halogenated Organic Compounds, Volume 10 covers three groups of Halogenated Organic Compounds (Chlorinated, Brominated, and Fluorinated Compounds) that are legacy and emerging contaminants, providing background information, characteristics, physicochemical properties, environmental contamination, and human exposure. Specific chapters covered in this release include Perspective on Halogenated Organic Compounds, The Neurotoxicity of Polychlorinated Biphenyls (PCBs), Neuroendocrine Effects of Polychlorinated Biphenyls (PCBs), Mechanisms of PCB Neurotoxicity: AHR and THR Dogma meet RYR reality, Microbiome and the Neurotoxicity of Brominated Flame Retardants (BFRs), and much more.

Other chapters cover Neuroendocrine Effects of Brominated Flame Retardants (BFRs), Focused on Polybrominated Diphenyl Ethers (PBDEs), Neurochemical Effects of Halogenated Organic Compounds: Possible Mode(s) of action and Structure-Activity Relationships, The Neurotoxic Effects of Perfluoroalkyl Substances (PFAS) in Animal Models and Human Cohorts, Neurochemical Mechanisms of Perfluoroalkyl Substances (PFAS) Neurotoxic Action, and Future Directions and Regulatory aspects of Halogenated Organic Compounds.

  • Presents the latest on the Neurotoxicity of Halogenated Organic Compounds: Epidemiological, Behavioral and other effects
  • Covers Neurochemical and Neuroendocrine effects of Halogenated Organic Compounds
  • Provides Regulatory aspects of Halogenated Organic Compounds

1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Chapter One: Perspective on halogenated organic compounds - p. 1 8. Chapter Two: The neurotoxicity of polychlorinated biphenyls (PCBs) - p. 27 9. Chapter Three: Neuroendocrine effects of polychlorinated biphenyls (PCBs) - p. 81 10. Chapter Four: Ryanodine receptor-dependent mechanisms of PCB developmental neurotoxicity - p. 137 11. Chapter Five: The microbiome/microbiota and the neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants - p. 179 12. Chapter Six: Neuroendocrine effects of brominated flame retardants, focused on polybrominated diphenyl ethers - p. 209 13. Chapter Seven: Neurochemical effects of halogenated organic compounds: Possible adverse outcome pathways and structure–activity relationships - p. 279 14. Chapter Eight: Neurotoxicity of poly- and perfluoroalkyl substances (PFAS): Epidemiological and rodent studies of behavioral outcomes - p. 325 15. Chapter Nine: Neurochemical mechanisms of perfluoroalkyl substances (PFAS) neurotoxic action - p. 367 16. Chapter Ten: Risk assessment, risk management, and regulation of halogenated organic chemicals: Current practice and future directions - p. 399

Descripcion
Descripción

Neurotoxicity of Halogenated Organic Compounds, Volume 10 covers three groups of Halogenated Organic Compounds (Chlorinated, Brominated, and Fluorinated Compounds) that are legacy and emerging contaminants, providing background information, characteristics, physicochemical properties, environmental contamination, and human exposure. Specific chapters covered in this release include Perspective on Halogenated Organic Compounds, The Neurotoxicity of Polychlorinated Biphenyls (PCBs), Neuroendocrine Effects of Polychlorinated Biphenyls (PCBs), Mechanisms of PCB Neurotoxicity: AHR and THR Dogma meet RYR reality, Microbiome and the Neurotoxicity of Brominated Flame Retardants (BFRs), and much more.

Other chapters cover Neuroendocrine Effects of Brominated Flame Retardants (BFRs), Focused on Polybrominated Diphenyl Ethers (PBDEs), Neurochemical Effects of Halogenated Organic Compounds: Possible Mode(s) of action and Structure-Activity Relationships, The Neurotoxic Effects of Perfluoroalkyl Substances (PFAS) in Animal Models and Human Cohorts, Neurochemical Mechanisms of Perfluoroalkyl Substances (PFAS) Neurotoxic Action, and Future Directions and Regulatory aspects of Halogenated Organic Compounds.

  • Presents the latest on the Neurotoxicity of Halogenated Organic Compounds: Epidemiological, Behavioral and other effects
  • Covers Neurochemical and Neuroendocrine effects of Halogenated Organic Compounds
  • Provides Regulatory aspects of Halogenated Organic Compounds

1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. Chapter One: Perspective on halogenated organic compounds - p. 1 8. Chapter Two: The neurotoxicity of polychlorinated biphenyls (PCBs) - p. 27 9. Chapter Three: Neuroendocrine effects of polychlorinated biphenyls (PCBs) - p. 81 10. Chapter Four: Ryanodine receptor-dependent mechanisms of PCB developmental neurotoxicity - p. 137 11. Chapter Five: The microbiome/microbiota and the neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants - p. 179 12. Chapter Six: Neuroendocrine effects of brominated flame retardants, focused on polybrominated diphenyl ethers - p. 209 13. Chapter Seven: Neurochemical effects of halogenated organic compounds: Possible adverse outcome pathways and structure–activity relationships - p. 279 14. Chapter Eight: Neurotoxicity of poly- and perfluoroalkyl substances (PFAS): Epidemiological and rodent studies of behavioral outcomes - p. 325 15. Chapter Nine: Neurochemical mechanisms of perfluoroalkyl substances (PFAS) neurotoxic action - p. 367 16. Chapter Ten: Risk assessment, risk management, and regulation of halogenated organic chemicals: Current practice and future directions - p. 399

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