Develop the strong foundation in pathophysiology you need to guide your patient care! Exploring the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders, Pathophysiology, 7th Edition focuses on the major alterations in the homeostasis of body systems to provide you with a unifying framework. Current scientific findings and relevant global research are integrated throughout the book, with chapters organized by body system, beginning with an illustrated review of anatomy and normal physiology. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Practical learning resources emphasize critical thinking and help simplify this rigorous subject. Updated, full-color illustrations and photos throughout enable you to visualize disease and disease processes and gain a clearer understanding of the material.
1. 1. Introduction to Pathophysiology - p. 1 2. 2. Homeostasis, Allostasis, and Adaptive Responses to Stressors - p. 12 3. Unit II. Cellular Function - p. 26 4. 3. Cell Structure and Function - p. 27 5. 4. Cell Injury, Aging, and Death - p. 62 6. 5. Genome Structure, Regulation, and Tissue Differentiation - p. 80 7. 6. Genetic and Developmental Disorders - p. 97 8. 7. Neoplasia - p. 120 9. Unit III. Defense - p. 145 10. 8. Infectious Processes - p. 146 11. 9. Inflammation and Immunity - p. 163 12. 10. Alterations in Immune Function - p. 200 13. 11. Malignant Disorders of White Blood Cells - p. 222 14. 12. HIV Disease and AIDS - p. 240 15. Unit IV. Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure - p. 268 16. 13. Alterations in Oxygen Transport - p. 269 17. 14. Alterations in Hemostasis and Blood Coagulation - p. 304 18. 15. Alterations in Blood Flow - p. 319 19. 16. Alterations in Blood Pressure - p. 343 20. Unit V. Cardiac Function - p. 360 21. 17. Cardiac Function - p. 361 22. 18. Alterations in Cardiac Function - p. 389 23. 19. Heart Failure and Dysrhythmias: Common Sequelae of Cardiac Diseases - p. 420 24. 20. Shock - p. 443 25. Unit VI. Respiratory Function - p. 460 26. 21. Respiratory Function and Alterations in Gas Exchange - p. 461 27. 22. Obstructive Pulmonary Disorders - p. 487 28. 23. Restrictive Pulmonary Disorders - p. 508 29. Unit VII. Fluid, Electrolyte, and Acid–Base Homeostasis - p. 530 30. 24. Fluid and Electrolyte Homeostasis and Imbalances - p. 531 31. 25. Acid–Base Homeostasis and Imbalances - p. 551 32. Unit VIII. Renal and Bladder Function - p. 560 33. 26. Renal Function - p. 561 34. 27. Intrarenal Disorders - p. 584 35. 28. Acute Kidney Injury and Chronic Kidney Disease - p. 603 36. 29. Disorders of the Lower Urinary Tract - p. 620 37. Unit IX. Genital and Reproductive Function - p. 635 38. 30. Male Genital and Reproductive Function - p. 636 39. 31. Alterations in Male Genital and Reproductive Function - p. 651 40. 32. Female Genital and Reproductive Function - p. 667 41. 33. Alterations in Female Genital and Reproductive Function - p. 682 42. 34. Sexually Transmitted Infections - p. 701 43. Unit X. Gastrointestinal Function - p. 708 44. 35. Gastrointestinal Function - p. 709 45. 36. Gastrointestinal Disorders - p. 732 46. 37. Alterations in Function of the Gallbladder and Exocrine Pancreas - p. 755 47. 38. Liver Diseases - p. 767 48. Unit XI. Endocrine Function, Metabolism, and Nutrition - p. 796 49. 39. Endocrine Physiology and Mechanisms of Hypothalamic-Pituitary Regulation - p. 797 50. 40. Disorders of Endocrine Function - p. 813 51. 41. Diabetes Mellitus - p. 830 52. 42. Alterations in Metabolism and Nutrition - p. 854 53. Unit XII. Neural Function - p. 865 54. 43. Structure and Function of the Nervous System - p. 866 55. 44. Acute Disorders of Brain Function - p. 907 56. 45. Chronic Disorders of Neurologic Function - p. 934 57. 46. Alterations in Special Sensory Function - p. 957 58. 47. Pain - p. 976 59. Unit XIII. Neuropsychological Function - p. 990 60. 48. Neurobiology of Psychotic Illnesses - p. 991 61. 49. Neurobiology of Nonpsychotic Illnesses - p. 1009 62. Part IV. Musculoskeletal Support and Movement - p. 1020 63. 50. Structure and Function of the Musculoskeletal System - p. 1021 64. 51. Alterations in Musculoskeletal Function: Trauma, Infection, and Disease - p. 1040 65. 52. Alterations in Musculoskeletal Function: Rheumatic Disorders - p. 1062 66. Unit XV. Integumentary System - p. 1079 67. 53. Alterations in the Integumentary System - p. 1080 68. 54. Burn Injuries - p. 1115 69. Glossary - p. 1136 70. Index - p. 1167
Develop the strong foundation in pathophysiology you need to guide your patient care! Exploring the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders, Pathophysiology, 7th Edition focuses on the major alterations in the homeostasis of body systems to provide you with a unifying framework. Current scientific findings and relevant global research are integrated throughout the book, with chapters organized by body system, beginning with an illustrated review of anatomy and normal physiology. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Practical learning resources emphasize critical thinking and help simplify this rigorous subject. Updated, full-color illustrations and photos throughout enable you to visualize disease and disease processes and gain a clearer understanding of the material.
1. 1. Introduction to Pathophysiology - p. 1 2. 2. Homeostasis, Allostasis, and Adaptive Responses to Stressors - p. 12 3. Unit II. Cellular Function - p. 26 4. 3. Cell Structure and Function - p. 27 5. 4. Cell Injury, Aging, and Death - p. 62 6. 5. Genome Structure, Regulation, and Tissue Differentiation - p. 80 7. 6. Genetic and Developmental Disorders - p. 97 8. 7. Neoplasia - p. 120 9. Unit III. Defense - p. 145 10. 8. Infectious Processes - p. 146 11. 9. Inflammation and Immunity - p. 163 12. 10. Alterations in Immune Function - p. 200 13. 11. Malignant Disorders of White Blood Cells - p. 222 14. 12. HIV Disease and AIDS - p. 240 15. Unit IV. Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure - p. 268 16. 13. Alterations in Oxygen Transport - p. 269 17. 14. Alterations in Hemostasis and Blood Coagulation - p. 304 18. 15. Alterations in Blood Flow - p. 319 19. 16. Alterations in Blood Pressure - p. 343 20. Unit V. Cardiac Function - p. 360 21. 17. Cardiac Function - p. 361 22. 18. Alterations in Cardiac Function - p. 389 23. 19. Heart Failure and Dysrhythmias: Common Sequelae of Cardiac Diseases - p. 420 24. 20. Shock - p. 443 25. Unit VI. Respiratory Function - p. 460 26. 21. Respiratory Function and Alterations in Gas Exchange - p. 461 27. 22. Obstructive Pulmonary Disorders - p. 487 28. 23. Restrictive Pulmonary Disorders - p. 508 29. Unit VII. Fluid, Electrolyte, and Acid–Base Homeostasis - p. 530 30. 24. Fluid and Electrolyte Homeostasis and Imbalances - p. 531 31. 25. Acid–Base Homeostasis and Imbalances - p. 551 32. Unit VIII. Renal and Bladder Function - p. 560 33. 26. Renal Function - p. 561 34. 27. Intrarenal Disorders - p. 584 35. 28. Acute Kidney Injury and Chronic Kidney Disease - p. 603 36. 29. Disorders of the Lower Urinary Tract - p. 620 37. Unit IX. Genital and Reproductive Function - p. 635 38. 30. Male Genital and Reproductive Function - p. 636 39. 31. Alterations in Male Genital and Reproductive Function - p. 651 40. 32. Female Genital and Reproductive Function - p. 667 41. 33. Alterations in Female Genital and Reproductive Function - p. 682 42. 34. Sexually Transmitted Infections - p. 701 43. Unit X. Gastrointestinal Function - p. 708 44. 35. Gastrointestinal Function - p. 709 45. 36. Gastrointestinal Disorders - p. 732 46. 37. Alterations in Function of the Gallbladder and Exocrine Pancreas - p. 755 47. 38. Liver Diseases - p. 767 48. Unit XI. Endocrine Function, Metabolism, and Nutrition - p. 796 49. 39. Endocrine Physiology and Mechanisms of Hypothalamic-Pituitary Regulation - p. 797 50. 40. Disorders of Endocrine Function - p. 813 51. 41. Diabetes Mellitus - p. 830 52. 42. Alterations in Metabolism and Nutrition - p. 854 53. Unit XII. Neural Function - p. 865 54. 43. Structure and Function of the Nervous System - p. 866 55. 44. Acute Disorders of Brain Function - p. 907 56. 45. Chronic Disorders of Neurologic Function - p. 934 57. 46. Alterations in Special Sensory Function - p. 957 58. 47. Pain - p. 976 59. Unit XIII. Neuropsychological Function - p. 990 60. 48. Neurobiology of Psychotic Illnesses - p. 991 61. 49. Neurobiology of Nonpsychotic Illnesses - p. 1009 62. Part IV. Musculoskeletal Support and Movement - p. 1020 63. 50. Structure and Function of the Musculoskeletal System - p. 1021 64. 51. Alterations in Musculoskeletal Function: Trauma, Infection, and Disease - p. 1040 65. 52. Alterations in Musculoskeletal Function: Rheumatic Disorders - p. 1062 66. Unit XV. Integumentary System - p. 1079 67. 53. Alterations in the Integumentary System - p. 1080 68. 54. Burn Injuries - p. 1115 69. Glossary - p. 1136 70. Index - p. 1167
