In this issue of Clinics in Perinatology, guest editor Dr. Lina Chalak brings her considerable expertise to the topic of Perinatal Asphyxia: Moving the Needle. Top experts discuss current clinical information on perinatal asphyxia, giving perinatologists they guidance they need to improve outcomes in newborns, while looking at results from clinical trials, neuroimaging biomarkers, and low-resource settings.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. CME Accreditation Page - p. xv 7. Forthcoming Issues - p. xvii 8. Foreword - p. xix 9. Preface - p. xxi 10. Causes and Terminology in Neonatal Encephalopathy: What is in a Name? Neonatal Encephalopathy, Hypoxic-ischemic Encephalopathy or Perinatal Asphyxia - p. 521 11. Neonatal Encephalopathy is a Complex Phenotype Representing Reproductive and Pregnancy Exposome Effects on the Maternal-Placental-Fetal Triad - p. 535 12. Uncovering the Role of Inflammation with Asphyxia in the Newborn - p. 551 13. Reverse Therapy: Impact of Hyperthermia and Rewarming on Newborn Outcomes - p. 565 14. Treating Seizures and Improving Newborn Outcomes for Infants with Hypoxic-Ischemic Encephalopathy - p. 573 15. Hypothermia for Hypoxic-ischemic Encephalopathy: Second-generation Trials to Address Gaps in Knowledge - p. 587 16. A New Horizon for Understanding the Comparative Effectiveness for Cooling Prospectively Infants with Mild Encephalopathy - p. 605 17. Key Inflammatory Biomarkers in Perinatal Asphyxia: A Comprehensive Review - p. 617 18. Advances in Neuroimaging Biomarkers and Scoring - p. 629 19. Advances in Electroencephalographic Biomarkers of Neonatal Hypoxic Ischemic Encephalopathy - p. 649 20. Moving the Needle in Low-Resource Settings: Is Hypothermia a Friend or a Foe? - p. 665 21. Long-Term Outcomes Following Hypoxic Ischemic Encephalopathy - p. 683 22. Communicating with Parents About Therapeutic Hypothermia and Hypoxic Ischemic Encephalopathy - p. 711 23. Ethical and Legal Perspectives on the Treatment of Hypoxic Ischemic Encephalopathy in the Newborn - p. 725 24. Pipeline to Neonatal Clinical Transformation: The Importance of Preclinical Data - p. 735
In this issue of Clinics in Perinatology, guest editor Dr. Lina Chalak brings her considerable expertise to the topic of Perinatal Asphyxia: Moving the Needle. Top experts discuss current clinical information on perinatal asphyxia, giving perinatologists they guidance they need to improve outcomes in newborns, while looking at results from clinical trials, neuroimaging biomarkers, and low-resource settings.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. CME Accreditation Page - p. xv 7. Forthcoming Issues - p. xvii 8. Foreword - p. xix 9. Preface - p. xxi 10. Causes and Terminology in Neonatal Encephalopathy: What is in a Name? Neonatal Encephalopathy, Hypoxic-ischemic Encephalopathy or Perinatal Asphyxia - p. 521 11. Neonatal Encephalopathy is a Complex Phenotype Representing Reproductive and Pregnancy Exposome Effects on the Maternal-Placental-Fetal Triad - p. 535 12. Uncovering the Role of Inflammation with Asphyxia in the Newborn - p. 551 13. Reverse Therapy: Impact of Hyperthermia and Rewarming on Newborn Outcomes - p. 565 14. Treating Seizures and Improving Newborn Outcomes for Infants with Hypoxic-Ischemic Encephalopathy - p. 573 15. Hypothermia for Hypoxic-ischemic Encephalopathy: Second-generation Trials to Address Gaps in Knowledge - p. 587 16. A New Horizon for Understanding the Comparative Effectiveness for Cooling Prospectively Infants with Mild Encephalopathy - p. 605 17. Key Inflammatory Biomarkers in Perinatal Asphyxia: A Comprehensive Review - p. 617 18. Advances in Neuroimaging Biomarkers and Scoring - p. 629 19. Advances in Electroencephalographic Biomarkers of Neonatal Hypoxic Ischemic Encephalopathy - p. 649 20. Moving the Needle in Low-Resource Settings: Is Hypothermia a Friend or a Foe? - p. 665 21. Long-Term Outcomes Following Hypoxic Ischemic Encephalopathy - p. 683 22. Communicating with Parents About Therapeutic Hypothermia and Hypoxic Ischemic Encephalopathy - p. 711 23. Ethical and Legal Perspectives on the Treatment of Hypoxic Ischemic Encephalopathy in the Newborn - p. 725 24. Pipeline to Neonatal Clinical Transformation: The Importance of Preclinical Data - p. 735
