Pharmacology for Health Professionals
1. Unit 1. Introduction to Pharmacology - p. xxii 2. 1. Drugs and medicines - p. 1 3. 2. Clinical, ethical and legal foundations of pharmacotherapy - p. 32 4. Unit 2. Principles of Pharmacology - p. 66 5. 3. Molecular drug targets and pharmacodynamics - p. 67 6. 4. Drug absorption, distribution, metabolism and excretion - p. 81 7. 5. Pharmacokinetics and dosing regimens - p. 101 8. 6. Precision medicine - p. 113 9. 7. Adverse drug reactions and drug interactions - p. 123 10. Unit 3. Drugs Affecting the Peripheral Nervous System - p. 132 11. 8. Drugs affecting cholinergic transmission - p. 133 12. 9. Drugs affecting noradrenergic transmission - p. 162 13. Unit 4. Drugs Affecting the Heart and Vascular System - p. 182 14. 10. Drugs affecting cardiac function - p. 183 15. 11. Drugs affecting vascular smooth muscle - p. 209 16. 12. Lipid-lowering drugs - p. 234 17. 13. Drugs affecting thrombosis and haemostasis - p. 249 18. 14. Drugs affecting the haemopoietic system - p. 268 19. Unit 5. Drugs Affecting the Respiratory System - p. 276 20. 15. Drugs used in respiratory disorders - p. 277 21. Introduction: The respiratory system, respiratory disease and its treatment - p. 278 22. Considerations for drug delivery to the airways: Drugs by inhalation - p. 281 23. Medical gases - p. 284 24. Respiratory stimulants and depressants - p. 287 25. Drugs affecting secretions and mucociliary transport - p. 287 26. Drugs affecting the nose - p. 290 27. Drug treatment of asthma - p. 293 28. Drug treatment of chronic obstructive pulmonary disease - p. 306 29. Drugs used in respiratory tract infections - p. 307 30. References - p. 314 31. Online resources - p. 315 32. Unit 6. Drugs Affecting the Gastrointestinal System - p. 316 33. 16. Drugs affecting the upper and lower gastrointestinal tract - p. 317 34. Unit 7. Drugs Affecting the Urinary System - p. 348 35. 17. Drugs affecting the kidney and bladder - p. 349 36. Unit 8. Drugs Affecting the Central Nervous System - p. 368 37. 18. Central nervous system overview and anaesthetics - p. 369 38. Introduction: The central nervous system - p. 370 39. General anaesthesia - p. 382 40. Local anaesthesia - p. 396 41. References - p. 408 42. Online resources - p. 408 43. 19. Analgesics - p. 410 44. 20. Antianxiety, sedative and hypnotic drugs - p. 442 45. 21. Antiepileptic drugs - p. 461 46. 22. Psychotropic agents - p. 483 47. 23. Central nervous system stimulants - p. 515 48. 24. Drugs for neurodegenerative disorders and headache - p. 527 49. 25. Drug dependence and social pharmacology - p. 552 50. Unit 9. Drugs Affecting the Endocrine System - p. 584 51. 26. The neuroendocrine system and pituitary gland - p. 585 52. 27. The thyroid gland, the parathyroid glands and bone disorders - p. 601 53. 28. The endocrine pancreas and diabetes mellitus - p. 626 54. 29. The adrenal cortex and corticosteroids - p. 647 55. Unit 10. Drugs Affecting the Reproductive System - p. 660 56. 30. Drugs affecting the female reproductive system - p. 661 57. 31. Drugs affecting the male reproductive system - p. 697 58. Unit 11. Drugs Used in Neoplastic Diseases - p. 714 59. 32. Principles of cancer therapy - p. 715 60. 33. Antineoplastic drugs - p. 731 61. Unit 12. Drugs Affecting Body Defences - p. 756 62. 34. Anti-inflammatory and immunomodulating drugs - p. 757 63. Unit 13. Drugs Affecting Microorganisms - p. 784 64. 35. Overview of antimicrobial chemotherapy and antibiotic resistance - p. 785 65. 36. Antibacterial drugs - p. 795 66. 37. Antifungal and antiviral drugs - p. 812 67. 38. Antiprotozoal, antimycobacterial and anthelmintic drugs - p. 832 68. Unit 14. Special Topics - p. 848 69. 39. Drugs affecting the skin - p. 849 70. 40. Drugs affecting the eye and ear - p. 877 71. 41. Drugs in aged care - p. 905 72. 42. Pharmacotherapy of obesity - p. 915 73. 43. Vaccinations - p. 925 74. 44. Complementary medicines - p. 945 75. Appendix 1: Abbreviations - p. 963 76. Appendix 2: Glossary - p. 967 77. Appendix 3: Common abbreviations and symbols used in prescriptions - p. 981 78. Appendix 4: Dose calculation examples - p. 983 79. Further readings - p. 989 80. Figure list - p. 997 81. Clinical focus box list - p. 1001 82. Drug monograph list - p. 1003 83. Figure and picture credits - p. 1004 84. Index - p. 1006
Pharmacology for Health Professionals
1. Unit 1. Introduction to Pharmacology - p. xxii 2. 1. Drugs and medicines - p. 1 3. 2. Clinical, ethical and legal foundations of pharmacotherapy - p. 32 4. Unit 2. Principles of Pharmacology - p. 66 5. 3. Molecular drug targets and pharmacodynamics - p. 67 6. 4. Drug absorption, distribution, metabolism and excretion - p. 81 7. 5. Pharmacokinetics and dosing regimens - p. 101 8. 6. Precision medicine - p. 113 9. 7. Adverse drug reactions and drug interactions - p. 123 10. Unit 3. Drugs Affecting the Peripheral Nervous System - p. 132 11. 8. Drugs affecting cholinergic transmission - p. 133 12. 9. Drugs affecting noradrenergic transmission - p. 162 13. Unit 4. Drugs Affecting the Heart and Vascular System - p. 182 14. 10. Drugs affecting cardiac function - p. 183 15. 11. Drugs affecting vascular smooth muscle - p. 209 16. 12. Lipid-lowering drugs - p. 234 17. 13. Drugs affecting thrombosis and haemostasis - p. 249 18. 14. Drugs affecting the haemopoietic system - p. 268 19. Unit 5. Drugs Affecting the Respiratory System - p. 276 20. 15. Drugs used in respiratory disorders - p. 277 21. Introduction: The respiratory system, respiratory disease and its treatment - p. 278 22. Considerations for drug delivery to the airways: Drugs by inhalation - p. 281 23. Medical gases - p. 284 24. Respiratory stimulants and depressants - p. 287 25. Drugs affecting secretions and mucociliary transport - p. 287 26. Drugs affecting the nose - p. 290 27. Drug treatment of asthma - p. 293 28. Drug treatment of chronic obstructive pulmonary disease - p. 306 29. Drugs used in respiratory tract infections - p. 307 30. References - p. 314 31. Online resources - p. 315 32. Unit 6. Drugs Affecting the Gastrointestinal System - p. 316 33. 16. Drugs affecting the upper and lower gastrointestinal tract - p. 317 34. Unit 7. Drugs Affecting the Urinary System - p. 348 35. 17. Drugs affecting the kidney and bladder - p. 349 36. Unit 8. Drugs Affecting the Central Nervous System - p. 368 37. 18. Central nervous system overview and anaesthetics - p. 369 38. Introduction: The central nervous system - p. 370 39. General anaesthesia - p. 382 40. Local anaesthesia - p. 396 41. References - p. 408 42. Online resources - p. 408 43. 19. Analgesics - p. 410 44. 20. Antianxiety, sedative and hypnotic drugs - p. 442 45. 21. Antiepileptic drugs - p. 461 46. 22. Psychotropic agents - p. 483 47. 23. Central nervous system stimulants - p. 515 48. 24. Drugs for neurodegenerative disorders and headache - p. 527 49. 25. Drug dependence and social pharmacology - p. 552 50. Unit 9. Drugs Affecting the Endocrine System - p. 584 51. 26. The neuroendocrine system and pituitary gland - p. 585 52. 27. The thyroid gland, the parathyroid glands and bone disorders - p. 601 53. 28. The endocrine pancreas and diabetes mellitus - p. 626 54. 29. The adrenal cortex and corticosteroids - p. 647 55. Unit 10. Drugs Affecting the Reproductive System - p. 660 56. 30. Drugs affecting the female reproductive system - p. 661 57. 31. Drugs affecting the male reproductive system - p. 697 58. Unit 11. Drugs Used in Neoplastic Diseases - p. 714 59. 32. Principles of cancer therapy - p. 715 60. 33. Antineoplastic drugs - p. 731 61. Unit 12. Drugs Affecting Body Defences - p. 756 62. 34. Anti-inflammatory and immunomodulating drugs - p. 757 63. Unit 13. Drugs Affecting Microorganisms - p. 784 64. 35. Overview of antimicrobial chemotherapy and antibiotic resistance - p. 785 65. 36. Antibacterial drugs - p. 795 66. 37. Antifungal and antiviral drugs - p. 812 67. 38. Antiprotozoal, antimycobacterial and anthelmintic drugs - p. 832 68. Unit 14. Special Topics - p. 848 69. 39. Drugs affecting the skin - p. 849 70. 40. Drugs affecting the eye and ear - p. 877 71. 41. Drugs in aged care - p. 905 72. 42. Pharmacotherapy of obesity - p. 915 73. 43. Vaccinations - p. 925 74. 44. Complementary medicines - p. 945 75. Appendix 1: Abbreviations - p. 963 76. Appendix 2: Glossary - p. 967 77. Appendix 3: Common abbreviations and symbols used in prescriptions - p. 981 78. Appendix 4: Dose calculation examples - p. 983 79. Further readings - p. 989 80. Figure list - p. 997 81. Clinical focus box list - p. 1001 82. Drug monograph list - p. 1003 83. Figure and picture credits - p. 1004 84. Index - p. 1006