Responsible Genomic Data Sharing: Challenges and Approaches brings together international experts in genomics research, bioinformatics and digital security who analyze common challenges in genomic data sharing, privacy preserving technologies, and best practices for large-scale genomic data sharing. Practical case studies, including the Global Alliance for Genomics and Health, the Beacon Network, and the Matchmaker Exchange, are discussed in-depth, illuminating pathways forward for new genomic data sharing efforts across research and clinical practice, industry and academia.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xi 6. Section I. Privacy challenges in genomic data sharing - p. xii 7. Chapter 1. Criticality of data sharing in genomic research and public views of genomic data sharing - p. 3 8. Chapter 2. Genomic data access policy models - p. 19 9. Chapter 3. Information leaks in genomic data: Inference attacks - p. 33 10. Chapter 4. Genealogical search using whole-genome genotype profiles - p. 51 11. Section II. Privacy-preserving techniques for responsible genomic data sharing - p. 94 12. Chapter 5. Homomorphic encryption - p. 97 13. Chapter 6. Secure multi-party computation - p. 123 14. Chapter 7. Game theory for privacy-preserving sharing of genomic data - p. 135 15. Chapter 8. Trusted execution environment with Intel SGX - p. 161 16. Index - p. 191
Responsible Genomic Data Sharing: Challenges and Approaches brings together international experts in genomics research, bioinformatics and digital security who analyze common challenges in genomic data sharing, privacy preserving technologies, and best practices for large-scale genomic data sharing. Practical case studies, including the Global Alliance for Genomics and Health, the Beacon Network, and the Matchmaker Exchange, are discussed in-depth, illuminating pathways forward for new genomic data sharing efforts across research and clinical practice, industry and academia.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xi 6. Section I. Privacy challenges in genomic data sharing - p. xii 7. Chapter 1. Criticality of data sharing in genomic research and public views of genomic data sharing - p. 3 8. Chapter 2. Genomic data access policy models - p. 19 9. Chapter 3. Information leaks in genomic data: Inference attacks - p. 33 10. Chapter 4. Genealogical search using whole-genome genotype profiles - p. 51 11. Section II. Privacy-preserving techniques for responsible genomic data sharing - p. 94 12. Chapter 5. Homomorphic encryption - p. 97 13. Chapter 6. Secure multi-party computation - p. 123 14. Chapter 7. Game theory for privacy-preserving sharing of genomic data - p. 135 15. Chapter 8. Trusted execution environment with Intel SGX - p. 161 16. Index - p. 191