The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance.
Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications.
Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry.
1. Spine Phenotypes - p. iii 2. Cover - p. iii 3. Title Page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Contributors - p. xiii 7. Foreword - p. xix 8. Foreword by Jeremy Fairbank MD FRCS, Professor of Spine Surgery and Honorary Departmental Senior Research Fellow, NDORMS, University of Oxford, UK - p. xxi 9. Preface - p. xxiii 10. Acknowledgments - p. xxv 11. Acknowledgment - p. xxvii 12. 1 Anatomy of the spine - p. 1 13. 2 Biomechanics of the spine - p. 35 14. 3 Biomechanical models to study spinal phenotypes - p. 47 15. 4 Animal models to study spinal intervertebral disc phenotypes - p. 67 16. 5 Imaging technologies of the spinal discs - p. 85 17. 6 Intervertebral disc degeneration - p. 105 18. 7 Disc space narrowing and osteophytes - p. 137 19. 8 Displacement of intervertebral discs - p. 155 20. 9 High-intensity zones and annular tears - p. 187 21. 10 Vertebral endplate abnormalities, defects, and changes - p. 203 22. 11 Vertebral bone marrow (Modic) changes - p. 223 23. 12 Ossification of the posterior longitudinal ligament - p. 253 24. 13 Lumbar spinal stenosis - p. 283 25. 14 Facet joints - p. 319 26. 15 Paraspinal muscles - p. 339 27. 16 Spinal alignment - p. 365 28. Index - p. 377
The era of big data and personalized spine care has arrived. Within that, imaging and clinical phenotypes are key in establishing personalized algorithms for patient care. This is particularly important in developing novel diagnostics and therapeutics as well as predicting outcomes and establishing preventative measures for various spinal disorders. Spine Phenotypes is a comprehensive resource that outlines phenotype descriptions, their imaging measurements and classifications, and provides an in-depth discussion regarding spine pathology and its clinical relevance.
Multiauthored, with multidisciplinary contributions from world leaders in the field of imaging, spine research, and clinical practice, each chapter is rich in visual depiction of imaging phenotypes, providing examples of some established phenotypic measurements with a range of normal and pathologic images and their clinical implications.
Spine Phenotypes will be a first of its kind reference for spine researchers, clinicians, and industry.
1. Spine Phenotypes - p. iii 2. Cover - p. iii 3. Title Page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Contributors - p. xiii 7. Foreword - p. xix 8. Foreword by Jeremy Fairbank MD FRCS, Professor of Spine Surgery and Honorary Departmental Senior Research Fellow, NDORMS, University of Oxford, UK - p. xxi 9. Preface - p. xxiii 10. Acknowledgments - p. xxv 11. Acknowledgment - p. xxvii 12. 1 Anatomy of the spine - p. 1 13. 2 Biomechanics of the spine - p. 35 14. 3 Biomechanical models to study spinal phenotypes - p. 47 15. 4 Animal models to study spinal intervertebral disc phenotypes - p. 67 16. 5 Imaging technologies of the spinal discs - p. 85 17. 6 Intervertebral disc degeneration - p. 105 18. 7 Disc space narrowing and osteophytes - p. 137 19. 8 Displacement of intervertebral discs - p. 155 20. 9 High-intensity zones and annular tears - p. 187 21. 10 Vertebral endplate abnormalities, defects, and changes - p. 203 22. 11 Vertebral bone marrow (Modic) changes - p. 223 23. 12 Ossification of the posterior longitudinal ligament - p. 253 24. 13 Lumbar spinal stenosis - p. 283 25. 14 Facet joints - p. 319 26. 15 Paraspinal muscles - p. 339 27. 16 Spinal alignment - p. 365 28. Index - p. 377
