A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, this book vividly demonstrates through first hand accounts how synthesis is really done and how by discovering new reactions, creating new designs and building molecules with atom and step economies, the advancement of the science of organic synthesis is providing solutions through function to create a better world.
1. Cover image 2. Title page 3. Table of Contents 4. Copyright 5. Dedication 6. Contributors 7. Foreword 8. Preface 9. Chapter 1 Total Syntheses of Solandelactones E and F 10. Chapter 2 The Marine Alkaloid Halichlorine 11. Chapter 3 An Adventure in Synthesis Inspired by the Pseudolaric Acids 12. Chapter 4 Total Synthesis of Papulacandin D 13. Chapter 5 Asymmetric Total Synthesis of the Antitumor Sesquiterpenoid (+)-Eremantholide A 14. Chapter 6 A Chemo- and Diastereoselective Ring Closing Metathesis Macrocyclization Approach to the Total Syntheses of Aigialomycin C and D 15. Chapter 7 Regio- and Stereoselective Metal-Catalyzed Reactions and Their Application to a Total Synthesis of (−)-Dactylolide 16. Chapter 8 Development of a General Approach to the Leucetta-Derived Alkaloids 17. Chapter 9 The Adventure of Abudinol and the Misadventure of Muzitone 18. Chapter 10 In Pursuit of an Elusive Target: 19. Chapter 11 Synthesis of the Lycopodium Alkaloid Lyconadin A 20. Chapter 12 Selective Alkane CH Bond Substitutions: Strategies for the Preparation of Functionalized Diamondoids (Nanodiamonds)* 21. Chapter 13 A Dipolar Cycloaddition Strategy for the Synthesis of 3,8-Diazabicyclo[3.2.1]Octane Tetrahydroisoquinoline Antitumor Antibiotics: The Total Synthesis of (−)-Lemonomycin 22. Chapter 14 Studies on the Synthesis of the Apoptolidins 23. Chapter 15 The Story Behind the Total Synthesis of Vibsanin E and 5-epi-Vibsanin E 24. Index
A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a second-hand analysis, this book vividly demonstrates through first hand accounts how synthesis is really done and how by discovering new reactions, creating new designs and building molecules with atom and step economies, the advancement of the science of organic synthesis is providing solutions through function to create a better world.
1. Cover image 2. Title page 3. Table of Contents 4. Copyright 5. Dedication 6. Contributors 7. Foreword 8. Preface 9. Chapter 1 Total Syntheses of Solandelactones E and F 10. Chapter 2 The Marine Alkaloid Halichlorine 11. Chapter 3 An Adventure in Synthesis Inspired by the Pseudolaric Acids 12. Chapter 4 Total Synthesis of Papulacandin D 13. Chapter 5 Asymmetric Total Synthesis of the Antitumor Sesquiterpenoid (+)-Eremantholide A 14. Chapter 6 A Chemo- and Diastereoselective Ring Closing Metathesis Macrocyclization Approach to the Total Syntheses of Aigialomycin C and D 15. Chapter 7 Regio- and Stereoselective Metal-Catalyzed Reactions and Their Application to a Total Synthesis of (−)-Dactylolide 16. Chapter 8 Development of a General Approach to the Leucetta-Derived Alkaloids 17. Chapter 9 The Adventure of Abudinol and the Misadventure of Muzitone 18. Chapter 10 In Pursuit of an Elusive Target: 19. Chapter 11 Synthesis of the Lycopodium Alkaloid Lyconadin A 20. Chapter 12 Selective Alkane CH Bond Substitutions: Strategies for the Preparation of Functionalized Diamondoids (Nanodiamonds)* 21. Chapter 13 A Dipolar Cycloaddition Strategy for the Synthesis of 3,8-Diazabicyclo[3.2.1]Octane Tetrahydroisoquinoline Antitumor Antibiotics: The Total Synthesis of (−)-Lemonomycin 22. Chapter 14 Studies on the Synthesis of the Apoptolidins 23. Chapter 15 The Story Behind the Total Synthesis of Vibsanin E and 5-epi-Vibsanin E 24. Index