1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Front Matter - p. iii 6. Copyright - p. iii 7. Preface - p. iii 8. Unit One: The Cell - p. iii 9. 1. Cellular Biology - p. 1 10. 2. Altered Cellular and Tissue Biology: Environmental Agents - p. 6 11. 3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases - p. 13 12. Unit Two: Genes and Geneenvironment Interaction - p. 19 13. 4. Genes and Genetic Diseases - p. 20 14. 5. Genes, Environment-Lifestyle, and Common Diseases - p. 25 15. 6. Epigenetics and Disease - p. 28 16. Unit Three: Mechanisms Of Self-Defense - p. 30 17. 7. Innate Immunity: Inflammation and Wound Healing - p. 31 18. 8. Adaptive Immunity - p. 38 19. 9. Alterations in Immunity and Inflammation - p. 42 20. 10. Infection - p. 47 21. 11. Stress and Disease - p. 54 22. Unit Four: Cellular Proliferation: Cancer - p. 56 23. 12. Cancer Biology - p. 57 24. 13. Cancer Epidemiology - p. 63 25. 14. Cancer in Children - p. 66 26. Unit Five: The Neurologic System - p. 68 27. 15. Structure and Function of the Neurologic System - p. 70 28. 16. Pain, Temperature Regulation, Sleep, and Sensory Function - p. 76 29. 17. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function - p. 83 30. 18. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction - p. 90 31. 19. Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders - p. 96 32. 20. Alterations of Neurologic Function in Children - p. 101 33. Unit Six: The Endocrine System - p. 103 34. 21. Mechanisms of Hormonal Regulation - p. 104 35. 22. Alterations of Hormonal Regulation - p. 110 36. 23. Obesity, Starvation, and Anorexia of Aging - p. 118 37. Unit Seven: The Reproductive Systems - p. 121 38. 24. Structure and Function of the Reproductive Systems - p. 122 39. 25. Alterations of the Female Reproductive System - p. 126 40. 26. Alterations of the Male Reproductive System - p. 133 41. 27. Sexually Transmitted Infections - p. 136 42. Unit Eight: The Hematologic System - p. 140 43. 28. Structure and Function of the Hematologic System - p. 141 44. 29. Alterations of Erythrocyte, Platelet, and Hemostatic Function - p. 148 45. 30. Alterations of Hematologic Function in Children - p. 159 46. Unit Nine: The Cardiovascular and Lymphatic Systems - p. 164 47. 31. Structure and Function of the Cardiovascular and Lymphatic Systems - p. 165 48. 32. Alterations of Cardiovascular Function - p. 172 49. 33. Alterations of Cardiovascular Function in Children - p. 182 50. Unit Ten: The Pulmonary System - p. 187 51. 34. Structure and Function of the Pulmonary System - p. 188 52. 35. Alterations of Pulmonary Function - p. 195 53. 36. Alterations of Pulmonary Function in Children - p. 204 54. Unit Eleven: The Renal and Urologic Systems - p. 209 55. 37. Structure and Function of the Renal and Urologic Systems - p. 210 56. 38. Alterations of Renal and Urinary Tract Function - p. 216 57. 39. Alterations of Renal and Urinary Tract Function in Children - p. 223 58. Unit Twelve: The Digestive System - p. 227 59. 40. Structure and Function of the Digestive System - p. 228 60. 41. Alterations of Digestive Function - p. 236 61. 42. Alterations of Digestive Function in Children - p. 244 62. Unit Thirteen: The Musculoskeletal System - p. 248 63. 43. Structure and Function of the Musculoskeletal System - p. 249 64. 44. Alterations of Musculoskeletal Function - p. 255 65. 45. Alterations of Musculoskeletal Function in Children - p. 264 66. Unit Fourteen: The Integumentary System - p. 269 67. 46. Structure, Function, and Disorders of the Integument - p. 270 68. 47. Alterations of the Integument in Children - p. 277 69. Unit Fifteen: Multiple Interacting Systems - p. 281 70. 48. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults - p. 282 71. 49. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children - p. 287 72. Answer Key - p. 292
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Front Matter - p. iii 6. Copyright - p. iii 7. Preface - p. iii 8. Unit One: The Cell - p. iii 9. 1. Cellular Biology - p. 1 10. 2. Altered Cellular and Tissue Biology: Environmental Agents - p. 6 11. 3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases - p. 13 12. Unit Two: Genes and Geneenvironment Interaction - p. 19 13. 4. Genes and Genetic Diseases - p. 20 14. 5. Genes, Environment-Lifestyle, and Common Diseases - p. 25 15. 6. Epigenetics and Disease - p. 28 16. Unit Three: Mechanisms Of Self-Defense - p. 30 17. 7. Innate Immunity: Inflammation and Wound Healing - p. 31 18. 8. Adaptive Immunity - p. 38 19. 9. Alterations in Immunity and Inflammation - p. 42 20. 10. Infection - p. 47 21. 11. Stress and Disease - p. 54 22. Unit Four: Cellular Proliferation: Cancer - p. 56 23. 12. Cancer Biology - p. 57 24. 13. Cancer Epidemiology - p. 63 25. 14. Cancer in Children - p. 66 26. Unit Five: The Neurologic System - p. 68 27. 15. Structure and Function of the Neurologic System - p. 70 28. 16. Pain, Temperature Regulation, Sleep, and Sensory Function - p. 76 29. 17. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function - p. 83 30. 18. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction - p. 90 31. 19. Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders - p. 96 32. 20. Alterations of Neurologic Function in Children - p. 101 33. Unit Six: The Endocrine System - p. 103 34. 21. Mechanisms of Hormonal Regulation - p. 104 35. 22. Alterations of Hormonal Regulation - p. 110 36. 23. Obesity, Starvation, and Anorexia of Aging - p. 118 37. Unit Seven: The Reproductive Systems - p. 121 38. 24. Structure and Function of the Reproductive Systems - p. 122 39. 25. Alterations of the Female Reproductive System - p. 126 40. 26. Alterations of the Male Reproductive System - p. 133 41. 27. Sexually Transmitted Infections - p. 136 42. Unit Eight: The Hematologic System - p. 140 43. 28. Structure and Function of the Hematologic System - p. 141 44. 29. Alterations of Erythrocyte, Platelet, and Hemostatic Function - p. 148 45. 30. Alterations of Hematologic Function in Children - p. 159 46. Unit Nine: The Cardiovascular and Lymphatic Systems - p. 164 47. 31. Structure and Function of the Cardiovascular and Lymphatic Systems - p. 165 48. 32. Alterations of Cardiovascular Function - p. 172 49. 33. Alterations of Cardiovascular Function in Children - p. 182 50. Unit Ten: The Pulmonary System - p. 187 51. 34. Structure and Function of the Pulmonary System - p. 188 52. 35. Alterations of Pulmonary Function - p. 195 53. 36. Alterations of Pulmonary Function in Children - p. 204 54. Unit Eleven: The Renal and Urologic Systems - p. 209 55. 37. Structure and Function of the Renal and Urologic Systems - p. 210 56. 38. Alterations of Renal and Urinary Tract Function - p. 216 57. 39. Alterations of Renal and Urinary Tract Function in Children - p. 223 58. Unit Twelve: The Digestive System - p. 227 59. 40. Structure and Function of the Digestive System - p. 228 60. 41. Alterations of Digestive Function - p. 236 61. 42. Alterations of Digestive Function in Children - p. 244 62. Unit Thirteen: The Musculoskeletal System - p. 248 63. 43. Structure and Function of the Musculoskeletal System - p. 249 64. 44. Alterations of Musculoskeletal Function - p. 255 65. 45. Alterations of Musculoskeletal Function in Children - p. 264 66. Unit Fourteen: The Integumentary System - p. 269 67. 46. Structure, Function, and Disorders of the Integument - p. 270 68. 47. Alterations of the Integument in Children - p. 277 69. Unit Fifteen: Multiple Interacting Systems - p. 281 70. 48. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults - p. 282 71. 49. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children - p. 287 72. Answer Key - p. 292
