Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches. This is a useful book for pharmaceutical scientists and basic and clinical scientists working in the research area of breast cancer and drug discovery both from academics and industry.
Worldwide, breast cancer is the most common cancer in women, however, breast cancer therapy is always challenging. This book aims to help researchers remain updated on the most targeted nanomedicine research available.
1. Chapter 1 : Breast cancer: introduction - p. Page ix 2. Chapter 2 : Basics of targeted nanodrug delivery of chemotherapeutics for breast cancer therapy - p. Page 20 3. Chapter 3 : Molecular targets of breast cancer for targeted nanomedicine - p. Page 39 4. Chapter 4 : Current status of nanomedicine for breast cancer treatment - p. Page 60 5. Chapter 5 : Targeted nanomedicine delivery to human epidermal growth receptor - p. Page 95 6. Chapter 6 : Cell-selective breast cancer targeting through estrogen receptors - p. Page 125 7. Chapter 7 : Folate receptor-mediated targeted breast cancer nanomedicine - p. Page 147 8. Chapter 8 : Hyaluronic receptors for developing breast cancer nanomedicine - p. Page 164 9. Chapter 9 : Targeting triple-negative breast cancers using nanomedicine - p. Page 190 10. Chapter 10 : Tumor adhesion molecule targeting for breast cancer nanomedicine - p. Page 241 11. Chapter 11 : Nanomedicine for targeting breast cancer stem cells - p. Page 272 12. Chapter 12 : Tumor microenvironment-mediated targeted drug delivery to breast cancer cells - p. Page 296 13. Chapter 13 : pH-responsive nanomedicine for breast cancer targeting - p. Page 324 14. Chapter 14 : Thermosensitive liposomes for targeted breast cancer therapy - p. Page 346 15. Chapter 15 : Hypoxia mediated targeted nanomedicine for breast cancer - p. Page 363 16. Chapter 16 : Redox-responsive nanomedicine for breast cancer therapy - p. Page 400 17. Chapter 17 : Targeted breast cancer nanotheranostics - p. Page 435 18. Chapter 18 : Radionanotheranostics for breast cancer diagnosis and therapy: recent advances and future opportunities - p. Page 458 19. Chapter 19 : Cell-penetrating peptides (CPPs) and peptide-drug conjugate systems (PDCs): site-specific delivery of bioactive(s) for effective breast cancer therapy - p. Page 497 20. Index - p. Page 526
Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches. This is a useful book for pharmaceutical scientists and basic and clinical scientists working in the research area of breast cancer and drug discovery both from academics and industry.
Worldwide, breast cancer is the most common cancer in women, however, breast cancer therapy is always challenging. This book aims to help researchers remain updated on the most targeted nanomedicine research available.
1. Chapter 1 : Breast cancer: introduction - p. Page ix 2. Chapter 2 : Basics of targeted nanodrug delivery of chemotherapeutics for breast cancer therapy - p. Page 20 3. Chapter 3 : Molecular targets of breast cancer for targeted nanomedicine - p. Page 39 4. Chapter 4 : Current status of nanomedicine for breast cancer treatment - p. Page 60 5. Chapter 5 : Targeted nanomedicine delivery to human epidermal growth receptor - p. Page 95 6. Chapter 6 : Cell-selective breast cancer targeting through estrogen receptors - p. Page 125 7. Chapter 7 : Folate receptor-mediated targeted breast cancer nanomedicine - p. Page 147 8. Chapter 8 : Hyaluronic receptors for developing breast cancer nanomedicine - p. Page 164 9. Chapter 9 : Targeting triple-negative breast cancers using nanomedicine - p. Page 190 10. Chapter 10 : Tumor adhesion molecule targeting for breast cancer nanomedicine - p. Page 241 11. Chapter 11 : Nanomedicine for targeting breast cancer stem cells - p. Page 272 12. Chapter 12 : Tumor microenvironment-mediated targeted drug delivery to breast cancer cells - p. Page 296 13. Chapter 13 : pH-responsive nanomedicine for breast cancer targeting - p. Page 324 14. Chapter 14 : Thermosensitive liposomes for targeted breast cancer therapy - p. Page 346 15. Chapter 15 : Hypoxia mediated targeted nanomedicine for breast cancer - p. Page 363 16. Chapter 16 : Redox-responsive nanomedicine for breast cancer therapy - p. Page 400 17. Chapter 17 : Targeted breast cancer nanotheranostics - p. Page 435 18. Chapter 18 : Radionanotheranostics for breast cancer diagnosis and therapy: recent advances and future opportunities - p. Page 458 19. Chapter 19 : Cell-penetrating peptides (CPPs) and peptide-drug conjugate systems (PDCs): site-specific delivery of bioactive(s) for effective breast cancer therapy - p. Page 497 20. Index - p. Page 526
