The Immunology of Horses and Donkeys offers a comprehensive overview of the immune systems of equids, bridging a critical gap by combining current research with foundational concepts and emphasizing both mechanisms and practical applications. The book covers immune development, disease resistance, vaccination, and immune disorders, supporting improved health management in horses and donkeys. Organized logically, it begins with the evolutionary history and domestication of equids and then explores immune ontogeny, innate and adaptive responses, and lymphoid tissue structure. Chapters detail the major histocompatibility complex, cytokine signaling, antigen-presenting cells, and mucosal immunity.
Additional sections address the microbiota, vaccine strategies, and immune responses to bacterial, viral, and parasitic infections, providing a holistic view of equine immune health. Users will find content that advances understanding in immunology, biomedical research, and veterinary medicine, supporting the development of better diagnostics, vaccines, and therapies. The book's clear, thorough approach benefits both scientific discovery and clinical application, ultimately improving equine health and informing broader mammalian immunology studies.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Preface - p. xv 8. Acknowledgments - p. xvii 9. Chapter 1. The evolution and domestication of horses and donkeys - p. 1 10. Chapter 2. Equine immune ontogeny, reproduction, and lactation - p. 21 11. Chapter 3. Innate immunity in the horse - p. 47 12. Chapter 4. The hematology of horses and donkeys - p. 71 13. Chapter 5. The equine sickness response - p. 95 14. Chapter 6. Equine cytokines - p. 123 15. Chapter 7. Equine antigen processing cells: Dendritic cells and macrophages - p. 147 16. Chapter 8. The equine lymphoid system - p. 169 17. Chapter 9. ELA—The equine major histocompatibility complex - p. 191 18. Chapter 10. Equine innate lymphoid cells - p. 209 19. Chapter 11. The equine B cell system - p. 227 20. Chapter 12. The central role of equine T cell systems - p. 255 21. Chapter 13. Immunity on equine body surfaces - p. 279 22. Chapter 14. The microbiota and the equine immune system - p. 303 23. Chapter 15. Horse and donkey vaccines - p. 329 24. Chapter 16. Immunity to selected equine bacterial and fungal diseases - p. 351 25. Chapter 17. Immunity to selected equine viruses - p. 377 26. Chapter 18. Immunity to selected equine parasites - p. 407 27. Chapter 19. Equine anaphylaxis and allergic diseases - p. 431 28. Chapter 20. Immune complex and other hypersensitivity diseases in horses - p. 461 29. Chapter 21. Equine cancer immunology and immunotherapy - p. 489 30. Chapter 22. Equine autoimmune diseases - p. 515 31. Chapter 23. Equine immunodeficiency diseases - p. 543 32. Chapter 24. Racing, exercise, and the equine immune system - p. 565 33. Chapter 25. Obesity, old age, and immunosenescence - p. 585 34. Abbreviations - p. 601 35. Glossary - p. 607 36. Index - p. 627
The Immunology of Horses and Donkeys offers a comprehensive overview of the immune systems of equids, bridging a critical gap by combining current research with foundational concepts and emphasizing both mechanisms and practical applications. The book covers immune development, disease resistance, vaccination, and immune disorders, supporting improved health management in horses and donkeys. Organized logically, it begins with the evolutionary history and domestication of equids and then explores immune ontogeny, innate and adaptive responses, and lymphoid tissue structure. Chapters detail the major histocompatibility complex, cytokine signaling, antigen-presenting cells, and mucosal immunity.
Additional sections address the microbiota, vaccine strategies, and immune responses to bacterial, viral, and parasitic infections, providing a holistic view of equine immune health. Users will find content that advances understanding in immunology, biomedical research, and veterinary medicine, supporting the development of better diagnostics, vaccines, and therapies. The book's clear, thorough approach benefits both scientific discovery and clinical application, ultimately improving equine health and informing broader mammalian immunology studies.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Preface - p. xv 8. Acknowledgments - p. xvii 9. Chapter 1. The evolution and domestication of horses and donkeys - p. 1 10. Chapter 2. Equine immune ontogeny, reproduction, and lactation - p. 21 11. Chapter 3. Innate immunity in the horse - p. 47 12. Chapter 4. The hematology of horses and donkeys - p. 71 13. Chapter 5. The equine sickness response - p. 95 14. Chapter 6. Equine cytokines - p. 123 15. Chapter 7. Equine antigen processing cells: Dendritic cells and macrophages - p. 147 16. Chapter 8. The equine lymphoid system - p. 169 17. Chapter 9. ELA—The equine major histocompatibility complex - p. 191 18. Chapter 10. Equine innate lymphoid cells - p. 209 19. Chapter 11. The equine B cell system - p. 227 20. Chapter 12. The central role of equine T cell systems - p. 255 21. Chapter 13. Immunity on equine body surfaces - p. 279 22. Chapter 14. The microbiota and the equine immune system - p. 303 23. Chapter 15. Horse and donkey vaccines - p. 329 24. Chapter 16. Immunity to selected equine bacterial and fungal diseases - p. 351 25. Chapter 17. Immunity to selected equine viruses - p. 377 26. Chapter 18. Immunity to selected equine parasites - p. 407 27. Chapter 19. Equine anaphylaxis and allergic diseases - p. 431 28. Chapter 20. Immune complex and other hypersensitivity diseases in horses - p. 461 29. Chapter 21. Equine cancer immunology and immunotherapy - p. 489 30. Chapter 22. Equine autoimmune diseases - p. 515 31. Chapter 23. Equine immunodeficiency diseases - p. 543 32. Chapter 24. Racing, exercise, and the equine immune system - p. 565 33. Chapter 25. Obesity, old age, and immunosenescence - p. 585 34. Abbreviations - p. 601 35. Glossary - p. 607 36. Index - p. 627