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In this issue of Infectious Disease Clinics of North America, guest editor Dr. Vincent B. Young brings his considerable expertise to the topic of Clostridioides difficile Infection. In the last decade there have been major changes in the diagnosis, epidemiology, and treatment of this important nosocomial infection. New treatments including new antibiotics and monoclonal antibodies have been developed to treat both initial episodes and recurrent CDI, and diagnostic and treatment guidelines have been created to reflect these developments. This issue addresses these changes to the clinical prevention, diagnosis, and treatment of CDI and also touches on advances in basic science that are more directly relevant to clinicians who encounter CDI in their daily professional practice.

  • Contains 14 relevant, practice-oriented topics including infection prevention approaches for Clostridioides difficile; advances in the medical treatment of Clostridioides difficile infection; microbiome therapeutics for CDI; predicting risk and outcomes in CDI; making sense of differing guidelines for CDI; and more
  • Provides in-depth clinical reviews on Clostridioides difficile Infection, offering actionable insights for clinical practice
  • Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Changes in the Epidemiology of Clostridioides difficile Infection - p. 567 9. Genomic Epidemiology of Clostridioides difficile - p. 581 10. The Transmission of Clostridioides (Clostridium) difficile with a One Health Perspective - p. 597 11. Diagnostic Approaches for Clostridioides difficile Infection - p. 611 12. Advances in the Medical Treatment of Clostridioides difficile Infection - p. 629 13. Management of Severe Clostridioides difficile Infection - p. 653 14. Microbiome Therapeutics for Clostridioides difficile Infection - p. 663 15. Infection Prevention Approaches for Clostridioides difficile - p. 685 16. Clostridioides difficile in Children - p. 709 17. Making Sense of Differing Guidelines for Clostridioides difficile Infection - p. 727 18. Predictive Modeling for Clostridioides difficile Infection: Current State of the Science, Clinical Applications, and Future Directions - p. 743 19. Advances in Understanding the Pathogenesis of Clostridioides difficile Infection - p. 761 20. In vitro and in Vivo Models for Understanding Clostridioides difficile - p. 781 21. Immune Aspects of Clostridioides difficile Infection and Vaccine Development - p. 801

Descripcion
Descripción

In this issue of Infectious Disease Clinics of North America, guest editor Dr. Vincent B. Young brings his considerable expertise to the topic of Clostridioides difficile Infection. In the last decade there have been major changes in the diagnosis, epidemiology, and treatment of this important nosocomial infection. New treatments including new antibiotics and monoclonal antibodies have been developed to treat both initial episodes and recurrent CDI, and diagnostic and treatment guidelines have been created to reflect these developments. This issue addresses these changes to the clinical prevention, diagnosis, and treatment of CDI and also touches on advances in basic science that are more directly relevant to clinicians who encounter CDI in their daily professional practice.

  • Contains 14 relevant, practice-oriented topics including infection prevention approaches for Clostridioides difficile; advances in the medical treatment of Clostridioides difficile infection; microbiome therapeutics for CDI; predicting risk and outcomes in CDI; making sense of differing guidelines for CDI; and more
  • Provides in-depth clinical reviews on Clostridioides difficile Infection, offering actionable insights for clinical practice
  • Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Changes in the Epidemiology of Clostridioides difficile Infection - p. 567 9. Genomic Epidemiology of Clostridioides difficile - p. 581 10. The Transmission of Clostridioides (Clostridium) difficile with a One Health Perspective - p. 597 11. Diagnostic Approaches for Clostridioides difficile Infection - p. 611 12. Advances in the Medical Treatment of Clostridioides difficile Infection - p. 629 13. Management of Severe Clostridioides difficile Infection - p. 653 14. Microbiome Therapeutics for Clostridioides difficile Infection - p. 663 15. Infection Prevention Approaches for Clostridioides difficile - p. 685 16. Clostridioides difficile in Children - p. 709 17. Making Sense of Differing Guidelines for Clostridioides difficile Infection - p. 727 18. Predictive Modeling for Clostridioides difficile Infection: Current State of the Science, Clinical Applications, and Future Directions - p. 743 19. Advances in Understanding the Pathogenesis of Clostridioides difficile Infection - p. 761 20. In vitro and in Vivo Models for Understanding Clostridioides difficile - p. 781 21. Immune Aspects of Clostridioides difficile Infection and Vaccine Development - p. 801

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