This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of endocrine pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Endocrine is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. iii 6. Contributing Authors - p. v 7. Preface - p. v 8. Acknowledgments - p. ix 9. Sections - p. xi 10. SECTION 1: THYROID - p. xiii 11. NONNEOPLASTIC - p. xiii 12. HEREDITARY/GENETIC/CONGENITAL - p. xiii 13. List of Tables - p. xiii 14. Chapter 1: Thyroglossal Duct Cyst - p. xiii 15. Chapter 2: Ectopic Thyroid - p. 7 16. Chapter 3: Solid Cell Nests - p. 11 17. Chapter 4: Dyshormonogenetic Goiter - p. 15 18. INFECTIOUS - p. 21 19. Chapter 5: Acute Thyroiditis - p. 21 20. AUTOIMMUNE/INFLAMMATORY - p. 25 21. Chapter 6: Subacute/Granulomatous Thyroiditis - p. 25 22. Chapter 7: Palpation Thyroiditis - p. 31 23. Chapter 8: IgG4-Related Thyroid Disease - p. 33 24. Chapter 9: Riedel Thyroiditis - p. 37 25. Chapter 10: Hashimoto Thyroiditis - p. 43 26. Chapter 11: Graves Disease (Diffuse Hyperplasia) - p. 51 27. Chapter 12: Amyloid Goiter - p. 59 28. REACTIVE - p. 65 29. Chapter 13: Pigments and Crystals, Thyroid - p. 65 30. Chapter 14: Post-FNA Site Changes, Thyroid - p. 71 31. NEOPLASTIC - p. 73 32. FOLLICULAR CELL-DERIVED NEOPLASMS - p. 73 33. Chapter 15: Thyroid Follicular Nodular Disease - p. 73 34. Chapter 16: Adenomatous Nodules - p. 79 35. Chapter 17: Follicular Thyroid Adenoma - p. 85 36. Chapter 18: Follicular Thyroid Adenoma With Papillary Architecture - p. 93 37. Chapter 19: Oncocytic Thyroid Adenoma - p. 97 38. Chapter 20: Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features - p. 101 39. Chapter 21: Hyalinizing Trabecular Tumor of Thyroid - p. 111 40. Chapter 22: Follicular Thyroid Carcinoma - p. 117 41. Chapter 23: Oncocytic Thyroid Carcinoma - p. 127 42. Chapter 24: Invasive Encapsulated Follicular Variant Papillary Thyroid Carcinoma - p. 131 43. Chapter 25: Kinase Fusion-Related Thyroid Carcinomas - p. 139 44. Chapter 26: Follicular Cell-Derived Thyroid Carcinoma, High Grade - p. 147 45. Chapter 27: Anaplastic Thyroid Carcinoma - p. 157 46. Chapter 28: Papillary Thyroid Carcinoma - p. 167 47. Chapter 29: Classic Papillary Thyroid Carcinoma - p. 181 48. Chapter 30: Infiltrative Follicular Variant Papillary Thyroid Carcinoma - p. 189 49. Chapter 31: Macrofollicular Papillary Thyroid Carcinoma - p. 193 50. Chapter 32: Diffuse Sclerosing Papillary Thyroid Carcinoma - p. 199 51. Chapter 33: Oncocytic Papillary Thyroid Carcinoma - p. 205 52. Chapter 34: Tall Cell Papillary Thyroid Carcinoma - p. 209 53. Chapter 35: Columnar Cell Papillary Thyroid Carcinoma - p. 217 54. Chapter 36: Clear Cell Papillary Thyroid Carcinoma - p. 221 55. Chapter 37: Solid/Trabecular Papillary Thyroid Carcinoma - p. 223 56. Chapter 38: Hobnail Papillary Thyroid Carcinoma - p. 227 57. Chapter 39: Warthin-Like Papillary Thyroid Carcinoma - p. 233 58. C-CELL-DERIVED TUMORS - p. 239 59. Chapter 40: C-Cell Hyperplasia - p. 239 60. Chapter 41: Medullary Thyroid Carcinoma - p. 245 61. MIXED MEDULLARY AND FOLLICULAR CELL CARCINOMA - p. 255 62. Chapter 42: Mixed Medullary and Follicular Cell-Derived Thyroid Carcinoma - p. 255 63. THYMIC TUMORS WITHIN THYROID - p. 259 64. Chapter 43: Spindle Epithelial Tumor With Thymus-Like Differentiation - p. 259 65. Chapter 44: Intrathyroid Thymic Carcinoma - p. 265 66. SALIVARY GLAND-LIKE THYROID TUMORS - p. 273 67. Chapter 45: Mucoepidermoid Carcinoma of Thyroid - p. 273 68. Chapter 46: Secretory Carcinoma of Salivary Gland Type - p. 277 69. HEMATOLYMPHOID TUMORS - p. 281 70. Chapter 47: Lymphoma, Thyroid - p. 281 71. Chapter 48: Follicular Dendritic Cell Sarcoma, Thyroid - p. 287 72. Chapter 49: Langerhans Cell Histiocytosis, Thyroid - p. 291 73. GERM CELL ORIGIN - p. 295 74. Chapter 50: Benign Thyroid Teratoma - p. 295 75. Chapter 51: Struma Ovarii, Struma Carcinoid, and Malignant Struma Ovarii - p. 301 76. EMBRYONAL THYROID TUMORS - p. 309 77. Chapter 52: Thyroblastoma - p. 309 78. MESENCHYMAL AND STROMAL TUMORS - p. 315 79. Chapter 53: Peripheral Nerve Sheath Tumor, Thyroid - p. 315 80. Chapter 54: Solitary Fibrous Tumor, Thyroid - p. 319 81. Chapter 55: Paraganglioma, Thyroid - p. 325 82. Chapter 56: Leiomyoma and Leiomyosarcoma, Thyroid - p. 331 83. Chapter 57: Angiosarcoma, Thyroid - p. 335 84. Chapter 58: Primary Ewing Sarcoma, Thyroid - p. 339 85. SECONDARY TUMORS WITHIN THYROID - p. 343 86. Chapter 59: Metastasis to Thyroid Gland - p. 343 87. TUMORS OF UNCERTAIN HISTOGENESIS - p. 349 88. Chapter 60: Cribriform Morular Thyroid Carcinoma - p. 349 89. Chapter 61: Sclerosing Mucoepidermoid Carcinoma With Eosinophilia - p. 359 90. MOLECULAR PATHOLOGY OF THYROID NEOPLASMS - p. 365 91. Chapter 62: Molecular Pathology of Thyroid Neoplasms - p. 365 92. PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF THYROID GLAND - p. 371 93. Chapter 63: Thyroid Carcinoma Protocol - p. 371 94. SECTION 2: PARATHYROID GLAND - p. 373 95. NONNEOPLASTIC - p. 373 96. Chapter 64: Primary Multiglandular Parathyroid Disease - p. 373 97. Chapter 65: Primary Parathyroid Clear Cell Hyperplasia - p. 385 98. Chapter 66: Secondary Parathyroid Hyperplasia - p. 389 99. Chapter 67: Tertiary Parathyroid Hyperplasia - p. 395 100. Chapter 68: Chronic Parathyroiditis - p. 399 101. NEOPLASTIC - p. 403 102. Chapter 69: Parathyroid Adenoma - p. 403 103. Chapter 70: Parathyroid Lipoadenoma - p. 411 104. Chapter 71: Atypical Parathyroid Tumor - p. 415 105. Chapter 72: Parathyroid Carcinoma - p. 421 106. Chapter 73: Metastasis to Parathyroid Gland - p. 431 107. SECTION 3: ADRENAL GLANDS - p. 435 108. ADRENAL CORTICAL NONNEOPLASTIC - p. 435 109. Chapter 74: Adrenal Heterotopia - p. 435 110. Chapter 75: Adrenal Hypoplasia and Malformations - p. 439 111. Chapter 76: Adrenal Cytomegaly - p. 443 112. Chapter 77: Infectious Disorders, Adrenal Glands - p. 445 113. Chapter 78: Autoimmune Adrenalitis - p. 449 114. Chapter 79: Adrenal Amyloidosis - p. 451 115. Chapter 80: Incidental Adrenal Nodules - p. 455 116. Chapter 81: Adrenal Cysts - p. 459 117. ADRENAL CORTICAL NEOPLASTIC - p. 465 118. Chapter 82: Adrenocortical Hyperplasia and Adrenocortical Nodular Disease - p. 465 119. Chapter 83: Primary Pigmented Nodular Adrenocortical Disease - p. 471 120. Chapter 84: Nonfunctioning Adrenal Cortical Adenoma - p. 477 121. Chapter 85: Aldosterone-Producing Adenoma - p. 479 122. Chapter 86: Cortisol-Secreting Adrenal Cortical Adenoma - p. 485 123. Chapter 87: Sex Hormone-Producing Adrenal Cortical Adenoma - p. 491 124. Chapter 88: Oncocytic Adrenal Cortical Adenoma - p. 493 125. Chapter 89: Adrenal Cortical Carcinoma - p. 497 126. Chapter 90: Adrenal Cortical Neoplasms in Children - p. 509 127. ADRENAL MEDULLA AND PARAGANGLIA - p. 517 128. Chapter 91: Adrenal Medullary Hyperplasia - p. 517 129. Chapter 92: Pheochromocytoma and Paraganglioma - p. 521 130. Chapter 93: Composite Pheochromocytoma and Composite Paraganglioma - p. 533 131. Chapter 94: Neuroblastic Tumors of Adrenal Gland - p. 539 132. ADRENAL MESENCHYMAL AND STROMAL TUMORS - p. 551 133. Chapter 95: Primary Adrenal Myelolipoma - p. 551 134. Chapter 96: Primary Adrenal Melanoma - p. 555 135. Chapter 97: Primary Adrenal Benign Connective Tissue Tumor - p. 559 136. Chapter 98: Primary Adrenal Angiosarcoma - p. 561 137. Chapter 99: Primary Adrenal Leiomyosarcoma - p. 565 138. Chapter 100: Metastasis to Adrenal Gland - p. 569 139. PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF ADRENAL GLAND - p. 573 140. Chapter 101: Adrenal Cortical Carcinoma Protocol - p. 573 141. SECTION 4: PITUITARY GLAND - p. 575 142. NONNEOPLASTIC - p. 575 143. Chapter 102: Hypophysitis, Pituitary Gland - p. 575 144. Chapter 103: Hyperplasia, Pituitary Gland - p. 581 145. Chapter 104: Sarcoidosis, Pituitary Gland - p. 583 146. Chapter 105: Infarction, Pituitary Gland - p. 587 147. Chapter 106: Sheehan Syndrome, Pituitary Gland - p. 589 148. Chapter 107: Cystic Lesions of Sellar Region - p. 591 149. NEOPLASTIC - p. 595 150. ANTERIOR NEUROENDOCRINE NEOPLASMS - p. 595 151. Chapter 108: Empty Sella Syndrome - p. 595 152. Chapter 109: Pituitary Neuroendocrine Tumor/Adenoma - p. 597 153. Chapter 110: Somatotroph PitNET/Adenoma - p. 603 154. Chapter 111: Lactotroph PitNET/Adenoma - p. 607 155. Chapter 112: Thyrotroph PitNET/Adenoma - p. 611 156. Chapter 113: Plurihormonal PitNET/Adenoma - p. 615 157. Chapter 114: Corticotroph PitNET/Adenoma - p. 619 158. Chapter 115: Gonadotroph PitNET/Adenoma - p. 623 159. Chapter 116: Null Cell PitNET/Adenoma - p. 627 160. Chapter 117: Metastatic Pituitary Neuroendocrine Tumor - p. 629 161. OTHER ANTERIOR PITUITARY TUMORS - p. 633 162. Chapter 118: Adamantinomatous Craniopharyngioma - p. 633 163. Chapter 119: Papillary Craniopharyngioma - p. 635 164. Chapter 120: Pituitary Blastoma - p. 637 165. POSTERIOR PITUITARY NEOPLASMS - p. 641 166. Chapter 121: Pituicytoma, Spindle Cell Oncocytoma, and Granular Cell Tumor of Sella - p. 641 167. NEURONAL TUMORS - p. 645 168. Chapter 122: Gangliocytoma - p. 645 169. Chapter 123: Neuronal Cell Tumors, Pituitary - p. 649 170. OTHER PITUITARY TUMORS - p. 651 171. Chapter 124: Metastasis to Pituitary Gland - p. 651 172. Chapter 125: Mesenchymal and Hematopoietic Tumors, Pituitary Gland - p. 653 173. PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH PRIMARY PITUITARY TUMORS - p. 657 174. Chapter 126: Protocol for Examination of Specimens From Patients With Primary Pituitary Tumors - p. 657 175. SECTION 5: ENDOCRINE PANCREAS - p. 661 176. Chapter 127: Pancreatic Neuroendocrine Neoplasms - p. 661 177. PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF ENDOCRINE PANCREAS - p. 673 178. Chapter 128: Pancreatic Neuroendocrine Carcinoma Protocol - p. 673 179. SECTION 6: ENDOCRINE SKIN - p. 675 180. Chapter 129: Merkel Cell Carcinoma - p. 675 181. SECTION 7: FAMILIAL TUMOR SYNDROMES - p. 687 182. MAJOR ENDOCRINE GLAND AFFECTED - p. 687 183. THYROID GLAND - p. 687 184. Chapter 130: DICER1 Syndrome - p. 687 185. Chapter 131: Familial Thyroid Carcinoma - p. 699 186. Chapter 132: McCune-Albright Syndrome - p. 705 187. Chapter 133: Multiple Endocrine Neoplasia Type 2 (MEN2) - p. 711 188. Chapter 134: Nonsyndromic Familial Follicular Cell-Derived Thyroid Carcinoma - p. 719 189. Chapter 135: PTEN Hamartoma Tumor Syndromes - p. 725 190. Chapter 136: Syndromic Familial Follicular Cell-Derived Thyroid Carcinoma - p. 733 191. PARATHYROID GLAND - p. 741 192. Chapter 137: Familial Isolated Hyperparathyroidism - p. 741 193. Chapter 138: Hyperparathyroidism-Jaw Tumor Syndrome - p. 745 194. Chapter 139: Multiple Endocrine Neoplasia Type 1 (MEN1) - p. 753 195. Chapter 140: Multiple Endocrine Neoplasia Type 4 (MEN4) - p. 761 196. ADRENAL GLAND AND PARAGANGLIA - p. 767 197. Chapter 141: Beckwith-Wiedemann Syndrome - p. 767 198. Chapter 142: Carney Complex - p. 775 199. Chapter 143: Hereditary Neuroblastoma - p. 783 200. Chapter 144: Hereditary Paraganglioma/Pheochromocytoma Syndromes - p. 787 201. Chapter 145: Multiple Endocrine Neoplasia Type 5, MAX-Related - p. 795 202. Chapter 146: Neurofibromatosis Type 1 - p. 797 203. Chapter 147: von Hippel-Lindau Syndrome - p. 805 204. Chapter 148: SDH-Deficient Pheochromocytoma and Paraganglioma - p. 813 205. PANCREAS - p. 819 206. Chapter 149: Glucagon Cell Hyperplasia and Neoplasia - p. 819 207. Chapter 150: Hereditary and Familial Pancreatic Cancer Syndrome - p. 823 208. Chapter 151: MAFA-Related Familial Insulinomatosis - p. 827 209. Chapter 152: Pancreatic Neuroendocrine Tumor Syndromes - p. 829 210. SECTION 8: PARANEOPLASTIC SYNDROMES - p. 839 211. Chapter 153: Ectopic (Paraneoplastic) Syndromes - p. 839 212. INDEX - p. 851
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of endocrine pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Endocrine is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference or as a reliable training resource.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. iii 6. Contributing Authors - p. v 7. Preface - p. v 8. Acknowledgments - p. ix 9. Sections - p. xi 10. SECTION 1: THYROID - p. xiii 11. NONNEOPLASTIC - p. xiii 12. HEREDITARY/GENETIC/CONGENITAL - p. xiii 13. List of Tables - p. xiii 14. Chapter 1: Thyroglossal Duct Cyst - p. xiii 15. Chapter 2: Ectopic Thyroid - p. 7 16. Chapter 3: Solid Cell Nests - p. 11 17. Chapter 4: Dyshormonogenetic Goiter - p. 15 18. INFECTIOUS - p. 21 19. Chapter 5: Acute Thyroiditis - p. 21 20. AUTOIMMUNE/INFLAMMATORY - p. 25 21. Chapter 6: Subacute/Granulomatous Thyroiditis - p. 25 22. Chapter 7: Palpation Thyroiditis - p. 31 23. Chapter 8: IgG4-Related Thyroid Disease - p. 33 24. Chapter 9: Riedel Thyroiditis - p. 37 25. Chapter 10: Hashimoto Thyroiditis - p. 43 26. Chapter 11: Graves Disease (Diffuse Hyperplasia) - p. 51 27. Chapter 12: Amyloid Goiter - p. 59 28. REACTIVE - p. 65 29. Chapter 13: Pigments and Crystals, Thyroid - p. 65 30. Chapter 14: Post-FNA Site Changes, Thyroid - p. 71 31. NEOPLASTIC - p. 73 32. FOLLICULAR CELL-DERIVED NEOPLASMS - p. 73 33. Chapter 15: Thyroid Follicular Nodular Disease - p. 73 34. Chapter 16: Adenomatous Nodules - p. 79 35. Chapter 17: Follicular Thyroid Adenoma - p. 85 36. Chapter 18: Follicular Thyroid Adenoma With Papillary Architecture - p. 93 37. Chapter 19: Oncocytic Thyroid Adenoma - p. 97 38. Chapter 20: Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features - p. 101 39. Chapter 21: Hyalinizing Trabecular Tumor of Thyroid - p. 111 40. Chapter 22: Follicular Thyroid Carcinoma - p. 117 41. Chapter 23: Oncocytic Thyroid Carcinoma - p. 127 42. Chapter 24: Invasive Encapsulated Follicular Variant Papillary Thyroid Carcinoma - p. 131 43. Chapter 25: Kinase Fusion-Related Thyroid Carcinomas - p. 139 44. Chapter 26: Follicular Cell-Derived Thyroid Carcinoma, High Grade - p. 147 45. Chapter 27: Anaplastic Thyroid Carcinoma - p. 157 46. Chapter 28: Papillary Thyroid Carcinoma - p. 167 47. Chapter 29: Classic Papillary Thyroid Carcinoma - p. 181 48. Chapter 30: Infiltrative Follicular Variant Papillary Thyroid Carcinoma - p. 189 49. Chapter 31: Macrofollicular Papillary Thyroid Carcinoma - p. 193 50. Chapter 32: Diffuse Sclerosing Papillary Thyroid Carcinoma - p. 199 51. Chapter 33: Oncocytic Papillary Thyroid Carcinoma - p. 205 52. Chapter 34: Tall Cell Papillary Thyroid Carcinoma - p. 209 53. Chapter 35: Columnar Cell Papillary Thyroid Carcinoma - p. 217 54. Chapter 36: Clear Cell Papillary Thyroid Carcinoma - p. 221 55. Chapter 37: Solid/Trabecular Papillary Thyroid Carcinoma - p. 223 56. Chapter 38: Hobnail Papillary Thyroid Carcinoma - p. 227 57. Chapter 39: Warthin-Like Papillary Thyroid Carcinoma - p. 233 58. C-CELL-DERIVED TUMORS - p. 239 59. Chapter 40: C-Cell Hyperplasia - p. 239 60. Chapter 41: Medullary Thyroid Carcinoma - p. 245 61. MIXED MEDULLARY AND FOLLICULAR CELL CARCINOMA - p. 255 62. Chapter 42: Mixed Medullary and Follicular Cell-Derived Thyroid Carcinoma - p. 255 63. THYMIC TUMORS WITHIN THYROID - p. 259 64. Chapter 43: Spindle Epithelial Tumor With Thymus-Like Differentiation - p. 259 65. Chapter 44: Intrathyroid Thymic Carcinoma - p. 265 66. SALIVARY GLAND-LIKE THYROID TUMORS - p. 273 67. Chapter 45: Mucoepidermoid Carcinoma of Thyroid - p. 273 68. Chapter 46: Secretory Carcinoma of Salivary Gland Type - p. 277 69. HEMATOLYMPHOID TUMORS - p. 281 70. Chapter 47: Lymphoma, Thyroid - p. 281 71. Chapter 48: Follicular Dendritic Cell Sarcoma, Thyroid - p. 287 72. Chapter 49: Langerhans Cell Histiocytosis, Thyroid - p. 291 73. GERM CELL ORIGIN - p. 295 74. Chapter 50: Benign Thyroid Teratoma - p. 295 75. Chapter 51: Struma Ovarii, Struma Carcinoid, and Malignant Struma Ovarii - p. 301 76. EMBRYONAL THYROID TUMORS - p. 309 77. Chapter 52: Thyroblastoma - p. 309 78. MESENCHYMAL AND STROMAL TUMORS - p. 315 79. Chapter 53: Peripheral Nerve Sheath Tumor, Thyroid - p. 315 80. Chapter 54: Solitary Fibrous Tumor, Thyroid - p. 319 81. Chapter 55: Paraganglioma, Thyroid - p. 325 82. Chapter 56: Leiomyoma and Leiomyosarcoma, Thyroid - p. 331 83. Chapter 57: Angiosarcoma, Thyroid - p. 335 84. Chapter 58: Primary Ewing Sarcoma, Thyroid - p. 339 85. SECONDARY TUMORS WITHIN THYROID - p. 343 86. Chapter 59: Metastasis to Thyroid Gland - p. 343 87. TUMORS OF UNCERTAIN HISTOGENESIS - p. 349 88. Chapter 60: Cribriform Morular Thyroid Carcinoma - p. 349 89. Chapter 61: Sclerosing Mucoepidermoid Carcinoma With Eosinophilia - p. 359 90. MOLECULAR PATHOLOGY OF THYROID NEOPLASMS - p. 365 91. Chapter 62: Molecular Pathology of Thyroid Neoplasms - p. 365 92. PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF THYROID GLAND - p. 371 93. Chapter 63: Thyroid Carcinoma Protocol - p. 371 94. SECTION 2: PARATHYROID GLAND - p. 373 95. NONNEOPLASTIC - p. 373 96. Chapter 64: Primary Multiglandular Parathyroid Disease - p. 373 97. Chapter 65: Primary Parathyroid Clear Cell Hyperplasia - p. 385 98. Chapter 66: Secondary Parathyroid Hyperplasia - p. 389 99. Chapter 67: Tertiary Parathyroid Hyperplasia - p. 395 100. Chapter 68: Chronic Parathyroiditis - p. 399 101. NEOPLASTIC - p. 403 102. Chapter 69: Parathyroid Adenoma - p. 403 103. Chapter 70: Parathyroid Lipoadenoma - p. 411 104. Chapter 71: Atypical Parathyroid Tumor - p. 415 105. Chapter 72: Parathyroid Carcinoma - p. 421 106. Chapter 73: Metastasis to Parathyroid Gland - p. 431 107. SECTION 3: ADRENAL GLANDS - p. 435 108. ADRENAL CORTICAL NONNEOPLASTIC - p. 435 109. Chapter 74: Adrenal Heterotopia - p. 435 110. Chapter 75: Adrenal Hypoplasia and Malformations - p. 439 111. Chapter 76: Adrenal Cytomegaly - p. 443 112. Chapter 77: Infectious Disorders, Adrenal Glands - p. 445 113. Chapter 78: Autoimmune Adrenalitis - p. 449 114. Chapter 79: Adrenal Amyloidosis - p. 451 115. Chapter 80: Incidental Adrenal Nodules - p. 455 116. Chapter 81: Adrenal Cysts - p. 459 117. ADRENAL CORTICAL NEOPLASTIC - p. 465 118. Chapter 82: Adrenocortical Hyperplasia and Adrenocortical Nodular Disease - p. 465 119. Chapter 83: Primary Pigmented Nodular Adrenocortical Disease - p. 471 120. Chapter 84: Nonfunctioning Adrenal Cortical Adenoma - p. 477 121. Chapter 85: Aldosterone-Producing Adenoma - p. 479 122. Chapter 86: Cortisol-Secreting Adrenal Cortical Adenoma - p. 485 123. Chapter 87: Sex Hormone-Producing Adrenal Cortical Adenoma - p. 491 124. Chapter 88: Oncocytic Adrenal Cortical Adenoma - p. 493 125. Chapter 89: Adrenal Cortical Carcinoma - p. 497 126. Chapter 90: Adrenal Cortical Neoplasms in Children - p. 509 127. ADRENAL MEDULLA AND PARAGANGLIA - p. 517 128. Chapter 91: Adrenal Medullary Hyperplasia - p. 517 129. Chapter 92: Pheochromocytoma and Paraganglioma - p. 521 130. Chapter 93: Composite Pheochromocytoma and Composite Paraganglioma - p. 533 131. Chapter 94: Neuroblastic Tumors of Adrenal Gland - p. 539 132. ADRENAL MESENCHYMAL AND STROMAL TUMORS - p. 551 133. Chapter 95: Primary Adrenal Myelolipoma - p. 551 134. Chapter 96: Primary Adrenal Melanoma - p. 555 135. Chapter 97: Primary Adrenal Benign Connective Tissue Tumor - p. 559 136. Chapter 98: Primary Adrenal Angiosarcoma - p. 561 137. Chapter 99: Primary Adrenal Leiomyosarcoma - p. 565 138. Chapter 100: Metastasis to Adrenal Gland - p. 569 139. PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF ADRENAL GLAND - p. 573 140. Chapter 101: Adrenal Cortical Carcinoma Protocol - p. 573 141. SECTION 4: PITUITARY GLAND - p. 575 142. NONNEOPLASTIC - p. 575 143. Chapter 102: Hypophysitis, Pituitary Gland - p. 575 144. Chapter 103: Hyperplasia, Pituitary Gland - p. 581 145. Chapter 104: Sarcoidosis, Pituitary Gland - p. 583 146. Chapter 105: Infarction, Pituitary Gland - p. 587 147. Chapter 106: Sheehan Syndrome, Pituitary Gland - p. 589 148. Chapter 107: Cystic Lesions of Sellar Region - p. 591 149. NEOPLASTIC - p. 595 150. ANTERIOR NEUROENDOCRINE NEOPLASMS - p. 595 151. Chapter 108: Empty Sella Syndrome - p. 595 152. Chapter 109: Pituitary Neuroendocrine Tumor/Adenoma - p. 597 153. Chapter 110: Somatotroph PitNET/Adenoma - p. 603 154. Chapter 111: Lactotroph PitNET/Adenoma - p. 607 155. Chapter 112: Thyrotroph PitNET/Adenoma - p. 611 156. Chapter 113: Plurihormonal PitNET/Adenoma - p. 615 157. Chapter 114: Corticotroph PitNET/Adenoma - p. 619 158. Chapter 115: Gonadotroph PitNET/Adenoma - p. 623 159. Chapter 116: Null Cell PitNET/Adenoma - p. 627 160. Chapter 117: Metastatic Pituitary Neuroendocrine Tumor - p. 629 161. OTHER ANTERIOR PITUITARY TUMORS - p. 633 162. Chapter 118: Adamantinomatous Craniopharyngioma - p. 633 163. Chapter 119: Papillary Craniopharyngioma - p. 635 164. Chapter 120: Pituitary Blastoma - p. 637 165. POSTERIOR PITUITARY NEOPLASMS - p. 641 166. Chapter 121: Pituicytoma, Spindle Cell Oncocytoma, and Granular Cell Tumor of Sella - p. 641 167. NEURONAL TUMORS - p. 645 168. Chapter 122: Gangliocytoma - p. 645 169. Chapter 123: Neuronal Cell Tumors, Pituitary - p. 649 170. OTHER PITUITARY TUMORS - p. 651 171. Chapter 124: Metastasis to Pituitary Gland - p. 651 172. Chapter 125: Mesenchymal and Hematopoietic Tumors, Pituitary Gland - p. 653 173. PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH PRIMARY PITUITARY TUMORS - p. 657 174. Chapter 126: Protocol for Examination of Specimens From Patients With Primary Pituitary Tumors - p. 657 175. SECTION 5: ENDOCRINE PANCREAS - p. 661 176. Chapter 127: Pancreatic Neuroendocrine Neoplasms - p. 661 177. PROTOCOL FOR EXAMINATION OF SPECIMENS FROM PATIENTS WITH CARCINOMA OF ENDOCRINE PANCREAS - p. 673 178. Chapter 128: Pancreatic Neuroendocrine Carcinoma Protocol - p. 673 179. SECTION 6: ENDOCRINE SKIN - p. 675 180. Chapter 129: Merkel Cell Carcinoma - p. 675 181. SECTION 7: FAMILIAL TUMOR SYNDROMES - p. 687 182. MAJOR ENDOCRINE GLAND AFFECTED - p. 687 183. THYROID GLAND - p. 687 184. Chapter 130: DICER1 Syndrome - p. 687 185. Chapter 131: Familial Thyroid Carcinoma - p. 699 186. Chapter 132: McCune-Albright Syndrome - p. 705 187. Chapter 133: Multiple Endocrine Neoplasia Type 2 (MEN2) - p. 711 188. Chapter 134: Nonsyndromic Familial Follicular Cell-Derived Thyroid Carcinoma - p. 719 189. Chapter 135: PTEN Hamartoma Tumor Syndromes - p. 725 190. Chapter 136: Syndromic Familial Follicular Cell-Derived Thyroid Carcinoma - p. 733 191. PARATHYROID GLAND - p. 741 192. Chapter 137: Familial Isolated Hyperparathyroidism - p. 741 193. Chapter 138: Hyperparathyroidism-Jaw Tumor Syndrome - p. 745 194. Chapter 139: Multiple Endocrine Neoplasia Type 1 (MEN1) - p. 753 195. Chapter 140: Multiple Endocrine Neoplasia Type 4 (MEN4) - p. 761 196. ADRENAL GLAND AND PARAGANGLIA - p. 767 197. Chapter 141: Beckwith-Wiedemann Syndrome - p. 767 198. Chapter 142: Carney Complex - p. 775 199. Chapter 143: Hereditary Neuroblastoma - p. 783 200. Chapter 144: Hereditary Paraganglioma/Pheochromocytoma Syndromes - p. 787 201. Chapter 145: Multiple Endocrine Neoplasia Type 5, MAX-Related - p. 795 202. Chapter 146: Neurofibromatosis Type 1 - p. 797 203. Chapter 147: von Hippel-Lindau Syndrome - p. 805 204. Chapter 148: SDH-Deficient Pheochromocytoma and Paraganglioma - p. 813 205. PANCREAS - p. 819 206. Chapter 149: Glucagon Cell Hyperplasia and Neoplasia - p. 819 207. Chapter 150: Hereditary and Familial Pancreatic Cancer Syndrome - p. 823 208. Chapter 151: MAFA-Related Familial Insulinomatosis - p. 827 209. Chapter 152: Pancreatic Neuroendocrine Tumor Syndromes - p. 829 210. SECTION 8: PARANEOPLASTIC SYNDROMES - p. 839 211. Chapter 153: Ectopic (Paraneoplastic) Syndromes - p. 839 212. INDEX - p. 851
