Gunderson & Tepper’s Clinical Radiation Oncology

1. Introduction - p. 836 2. Etiology and Epidemiology - p. 837 3. Early Detection and Prevention - p. 837 4. Pathology and Molecular Biology of Lung Cancer - p. 838 5. Carcinogenesis and Pathways of Spread - p. 841 6. Clinical Manifestations, Patient Evaluation, and Staging - p. 843 7. Primary Therapy - p. 846 8. Radiotherapy Treatment Planning and Techniques - p. 858 9. Systemic and Local Management of Metastatic Disease - p. 862 10. Controversies - p. 866 11. Conclusions - p. 866 12. References - p. 867.e1 13. 52 Uncommon Thoracic Tumors - p. 868 14. Thymic Tumors - p. 868 15. Pulmonary Carcinoid Tumors - p. 879 16. Mesothelioma - p. 885 17. Summary - p. 895 18. Acknowledgments - p. 895 19. References - p. 897.e1 20. Part D Gastrointestinal Tumors - p. 897.e12 21. 53 Overview - p. 898 22. 54 Esophagus-Gastric Cancer - p. 908 23. Introduction - p. 909 24. Epidemiology and Etiology - p. 909 25. Prevention and Early Detection - p. 909.e1 26. Biological Characteristics and Molecular Biology - p. 909.e1 27. Pathology and Pathways of Spread - p. 913 28. Primary Therapy - p. 913.e1 29. Locally Advanced Disease and Palliation - p. 933 30. Irradiation Techniques and Tolerances - p. 934 31. Treatment Algorithm, Challenges, and Future Possibilities - p. 942 32. References - p. 945.e1 33. 55 Pancreatic Cancer - p. 946 34. Introduction - p. 947 35. Epidemiology and Etiology - p. 947 36. Prevention and Early Detection - p. 948 37. Biologic Characteristics and Molecular Biology - p. 948 38. Pathology and Pathways of Spread - p. 948.e1 39. Clinical Manifestations, Patient Evaluation, and Staging - p. 951 40. Primary Therapy - p. 954 41. Locally Advanced Disease - p. 960.e2 42. Metastatic Disease and Palliation - p. 964.e1 43. Irradiation Techniques and Tolerance - p. 965.e1 44. Treatment Algorithm, Challenges, and Future Directions - p. 970 45. References - p. 972.e1 46. 56 Hepatobiliary Cancer - p. 973 47. 57 Colon Cancer - p. 995 48. 58 Rectal Cancer - p. 1011 49. Etiology and Epidemiology - p. 1011 50. Prevention and Early Detection - p. 1012 51. Biological Characteristics and Molecular Biology - p. 1012 52. Pathology and Pathways of Spread - p. 1013 53. Clinical Manifestations, Patient Evaluation, and Staging - p. 1014 54. Posttreatment Assessment - p. 1017 55. Primary and Adjuvant Therapy for Resectable Disease - p. 1017 56. Locally Advanced Disease and Palliation - p. 1028 57. Irradiation Techniques and Tolerance - p. 1033 58. Conclusions - p. 1035 59. References - p. 1036.e1 60. 59 Anal Carcinoma - p. 1037 61. Part E Genitourinary Tumors - p. 1050.e4 62. 60 Overview - p. 1051 63. 61 Prostate Cancer - p. 1054 64. Epidemiology and Etiology - p. 1054 65. Prevention and Early Detection - p. 1055.e1 66. Pathology and Pathways of Spread - p. 1057.e1 67. Histology - p. 1057.e1 68. Pathology of Prostate Cancer - p. 1057.e1 69. Clinical and Pathologic Stage Grouping - p. 1060 70. Predictive Factors - p. 1062 71. Clinical Manifestations, Patient Evaluation, Staging - p. 1067 72. Primary Therapy - p. 1072 73. Surgical Therapy - p. 1089.e1 74. Locally Advanced Disease - p. 1093 75. Adjuvant Versus Salvage Radiotherapy - p. 1102 76. Metastatic Disease - p. 1103 77. Irradiation Techniques - p. 1104.e1 78. Treatment Algorithm and Future Directions - p. 1112 79. References - p. 1114.e1 80. 62 Bladder Cancer - p. 1115 81. 63 Testicular Cancer - p. 1132 82. 64 Kidney and Ureteral Carcinoma - p. 1150 83. 65 Penile Cancer - p. 1170 84. Part F Gynecological Tumors - p. 1180.e2 85. 66 Overview - p. 1181 86. 67 Cervical Cancer - p. 1184 87. Epidemiology and Etiology - p. 1185 88. Prevention and Early Detection - p. 1185 89. Pathology and Pathways of Spread - p. 1186 90. Molecular Biology - p. 1187 91. Clinical Manifestations, Patient Evaluation, and Staging - p. 1188 92. Primary Therapy - p. 1190 93. Locally Advanced Disease and Palliation - p. 1199 94. Irradiation Techniques and Tolerance - p. 1200.e1 95. Treatment Algorithm, Conclusions, and FUTURE Possibilities - p. 1210 96. References - p. 1212.e1 97. 68 Endometrial Cancer - p. 1213 98. Epidemiology and Etiology - p. 1214 99. Prevention and Early Detection - p. 1215 100. Biological Characteristics/Molecular Biology - p. 1215 101. Pathology and Pathways of Spread - p. 1217 102. Clinical Manifestations, Patient Evaluation, and Staging - p. 1217.e1 103. Locally Advanced Disease and Palliation - p. 1229 104. Systemic Therapy for Recurrent or Metastatic Disease - p. 1231 105. Irradiation Techniques and Tolerance - p. 1234 106. Treatment Algorithm, Conclusions, and Challenges - p. 1240 107. References - p. 1242.e1 108. 69 Cancers of the Vulva and Vagina - p. 1243 109. Vulvar Cancer - p. 1245 110. Etiology and Epidemiology - p. 1245 111. Early Detection, Treatment and Prevention - p. 1245 112. Pathology and Pathways of Spread - p. 1246 113. Biology and Prognostic Factors - p. 1248 114. Clinical Manifestations, Patient Evaluation, and Staging - p. 1249 115. Primary Therapy - p. 1251 116. Locally Advanced Disease and Palliation - p. 1260 117. Irradiation Techniques and Tolerance - p. 1262 118. Challenges, Controversies, and Future Possibilities - p. 1264.e1 119. Miscellaneous Vulvar Malignancies - p. 1264.e1 120. Vaginal Cancer - p. 1267 121. Etiology and Epidemiology - p. 1266.e1 122. Prevention and Early Detection - p. 1266.e1 123. Pathology and Pathways of Spread - p. 1266.e1 124. Clinical Manifestations, Patient Evaluation, and Staging - p. 1266.e1 125. Primary Therapy - p. 1268 126. Locally Advanced Disease and Palliation - p. 1270 127. Irradiation Techniques and Tolerance - p. 1270 128. Treatment Algorithm and Future Possibilities - p. 1274 129. Nonsquamous Vaginal Malignancies - p. 1274 130. References - p. 1275.e1 131. 70 Ovarian Cancer - p. 1276 132. Part G Breast Cancer - p. 1296.e8 133. 71 Overview - p. 1297 134. 72 Noninvasive Breast Cancer - p. 1316 135. 73 Breast Cancer - p. 1325 136. Introduction - p. 1325 137. Pretreatment Evaluation - p. 1326 138. Surgical Techniques - p. 1325.e1 139. Breast-Conserving Surgery With Radiotherapy - p. 1325.e1 140. When to Use Nodal Irradiation - p. 1328.e1 141. Treatment Techniques - p. 1331 142. Radiotherapy Dose and Schedule Parameters - p. 1334 143. Accelerated Partial-Breast Irradiation - p. 1333.e1 144. Acute and Chronic Complications and Cosmetic Results - p. 1336 145. Patient Follow-Up - p. 1339 146. Treatment of Locoregional Failure - p. 1338.e1 147. Conclusions - p. 1338.e1 148. References - p. 1341.e1 149. 74 Locally Advanced and Inflammatory Breast Cancer - p. 1342 150. Part H Sarcoma and Benign Disease - p. 1358.e2 151. 75 Soft-Tissue Sarcoma - p. 1359 152. 76 Benign Diseases - p. 1386 153. Part I Childhood Cancers - p. 1397.e8 154. 77 Overview - p. 1398 155. 78 Central Nervous System Tumors in Children - p. 1403 156. 79 Pediatric Soft-Tissue Sarcomas - p. 1421 157. 80 Pediatric Sarcomas of Bone - p. 1431 158. 81 Wilms Tumor - p. 1442 159. 82 Retinoblastoma - p. 1453 160. 83 Neuroblastoma - p. 1460 161. 84 Pediatric Leukemia and Lymphoma - p. 1468 162. 85 Pediatric Hodgkin Lymphoma - p. 1477 163. 86 Rare Pediatric Tumors - p. 1497 164. Part J Lymphoma and Hematological Malignancies - p. 1510.e6 165. 87 Overview - p. 1511 166. 88 Hodgkin Lymphoma - p. 1516 167. 89 Non-Hodgkin Lymphoma - p. 1531 168. Introduction - p. 1531 169. Etiology and Epidemiology - p. 1531 170. Prevention and Early Detection - p. 1532 171. Biological Characteristics and Pathology - p. 1533 172. Clinical Manifestations, Patient Evaluation, and Staging Classification - p. 1537 173. Prognostic Factors - p. 1539 174. Principles of Management - p. 1539 175. Management of Distinct Disease Entities - p. 1541 176. Conclusion - p. 1553 177. References - p. 1554.e1 178. 90 Multiple Myeloma and Other Plasma Cell Neoplasms - p. 1555 179. 91 Mycosis Fungoides - p. 1564 180. Index - p. 1587