Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate.
In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures.
1. Resident Stem Cells and Regenerative Therapy - p. ii 2. Cover - p. ii 3. Dedication - p. ii 4. Title Page - p. iii 5. Copyright Page - p. iv 6. List of Contributors - p. xi 7. Foreword - p. xvii 8. Chapter 1 Book Overview - p. 1 9. Chapter 2 Cardiac Stem Cells: Fact or Fiction? - p. 5 10. Chapter 3 Resident Liver Stem Cells - p. 23 11. Chapter 4 Lung-Resident Stem Cells - p. 53 12. Chapter 5 Pancreatic Stem Cells and Regenerative Medicine of Endocrine Pancreas - p. 75 13. Chapter 6 Pericytes as a Source of MSCs - p. 105 14. Chapter 7 Resident Neural Stem Cells - p. 127 15. Chapter 8 Resident Stem Cells in Kidney Tissue - p. 159 16. Chapter 9 Skin Resident Stem Cells - p. 205 17. Chapter 10 Skeletal Resident Stem Cells - p. 251 18. Chapter 11 The Neural Crest and The Stem Cells of Neural Crest - p. 285 19. Chapter 12 Telocytes and Stem Cells∗ - p. 305 20. Chapter 13 Adipose Tissue Resident Stem Cells - p. 339 21. Chapter 14 Bone Marrow–Resident Stem Cells - p. 357 22. Index - p. 381
Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate.
In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures.
1. Resident Stem Cells and Regenerative Therapy - p. ii 2. Cover - p. ii 3. Dedication - p. ii 4. Title Page - p. iii 5. Copyright Page - p. iv 6. List of Contributors - p. xi 7. Foreword - p. xvii 8. Chapter 1 Book Overview - p. 1 9. Chapter 2 Cardiac Stem Cells: Fact or Fiction? - p. 5 10. Chapter 3 Resident Liver Stem Cells - p. 23 11. Chapter 4 Lung-Resident Stem Cells - p. 53 12. Chapter 5 Pancreatic Stem Cells and Regenerative Medicine of Endocrine Pancreas - p. 75 13. Chapter 6 Pericytes as a Source of MSCs - p. 105 14. Chapter 7 Resident Neural Stem Cells - p. 127 15. Chapter 8 Resident Stem Cells in Kidney Tissue - p. 159 16. Chapter 9 Skin Resident Stem Cells - p. 205 17. Chapter 10 Skeletal Resident Stem Cells - p. 251 18. Chapter 11 The Neural Crest and The Stem Cells of Neural Crest - p. 285 19. Chapter 12 Telocytes and Stem Cells∗ - p. 305 20. Chapter 13 Adipose Tissue Resident Stem Cells - p. 339 21. Chapter 14 Bone Marrow–Resident Stem Cells - p. 357 22. Index - p. 381
