The Pituitary, Fifth Edition continues the tradition of a cogent blend of basic science and clinical medicine. The comprehensive text written by expert pituitary scholars is devoted to the pathogenesis, diagnosis and treatment of pituitary disorders. The new fifth edition has been extensively revised to reflect the most recent data on new research advances in tumorigenesis and new therapeutic approaches for pituitary tumors, particularly in acromegaly and Cushing disease. Notably, new chapters devoted to the Pituitary-Immune Interface and Pituitary Radiotherapy have been included, along with a chapter on Aggressive Pituitary Adenomas developed to align with the WHOs Classification of Pituitary Tumors.
Furthermore, new authors have been invited, ensuring a fresh perspective on critical issues in the field. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders.
1. Introduction - p. 495 2. Classification - p. 495 3. Epidemiology and natural history - p. 496 4. Pathogenesis - p. 496 5. Clinical manifestations - p. 504 6. Diagnosis - p. 506 7. Treatment - p. 510 8. Special situations - p. 528 9. Chapter 17 Cushing's Disease - p. 545 10. Introduction - p. 545 11. Epidemiology - p. 545 12. Chronic pituitary ACTH and proopiomelanocortin peptide oversecretion - p. 545 13. Adrenal pathology in Cushing's disease - p. 555 14. ACTH-dependent spontaneous Cushing's syndromes - p. 555 15. ACTH-independent spontaneous Cushing's syndrome - p. 556 16. Iatrogenic Cushing's syndromes - p. 557 17. Clinical features - p. 557 18. Diagnosis of Cushing's disease - p. 559 19. Long-term outcomes of Cushing's disease - p. 561 20. Diagnostic approach - p. 562 21. Imaging - p. 569 22. Pitfalls in diagnosis - p. 571 23. Treatment - p. 576 24. Pituitary surgery and radiation - p. 577 25. Medical treatments - p. 579 26. Adrenal surgery - p. 581 27. Overall approach for treatment - p. 582 28. Chapter 18 Nonfunctioning and Gonadotrophin-Secreting Adenomas - p. 599 29. Chapter 19 Thyrotrophin-Secreting Pituitary Adenomas - p. 615 30. Chapter 20 Aggressive Pituitary Adenomas - p. 637 31. Chapter 21 Genetics of Pituitary Adenoma Syndromes - p. 649 32. Chapter 22 Nonpituitary Sellar Masses - p. 661 33. Chapter 23 Pituitary Imaging - p. 677 34. Chapter 24 Pituitary Surgery - p. 723 35. Chapter 25 Radiotherapy in the Management of Pituitary Adenomas - p. 753 36. Index - p. 765 37. Index - Continued - p. 774
The Pituitary, Fifth Edition continues the tradition of a cogent blend of basic science and clinical medicine. The comprehensive text written by expert pituitary scholars is devoted to the pathogenesis, diagnosis and treatment of pituitary disorders. The new fifth edition has been extensively revised to reflect the most recent data on new research advances in tumorigenesis and new therapeutic approaches for pituitary tumors, particularly in acromegaly and Cushing disease. Notably, new chapters devoted to the Pituitary-Immune Interface and Pituitary Radiotherapy have been included, along with a chapter on Aggressive Pituitary Adenomas developed to align with the WHOs Classification of Pituitary Tumors.
Furthermore, new authors have been invited, ensuring a fresh perspective on critical issues in the field. This extensive body of knowledge is useful for students, trainees, physicians, and scientists who need to understand critical pituitary functions and how to care for patients with pituitary disorders.
1. Introduction - p. 495 2. Classification - p. 495 3. Epidemiology and natural history - p. 496 4. Pathogenesis - p. 496 5. Clinical manifestations - p. 504 6. Diagnosis - p. 506 7. Treatment - p. 510 8. Special situations - p. 528 9. Chapter 17 Cushing's Disease - p. 545 10. Introduction - p. 545 11. Epidemiology - p. 545 12. Chronic pituitary ACTH and proopiomelanocortin peptide oversecretion - p. 545 13. Adrenal pathology in Cushing's disease - p. 555 14. ACTH-dependent spontaneous Cushing's syndromes - p. 555 15. ACTH-independent spontaneous Cushing's syndrome - p. 556 16. Iatrogenic Cushing's syndromes - p. 557 17. Clinical features - p. 557 18. Diagnosis of Cushing's disease - p. 559 19. Long-term outcomes of Cushing's disease - p. 561 20. Diagnostic approach - p. 562 21. Imaging - p. 569 22. Pitfalls in diagnosis - p. 571 23. Treatment - p. 576 24. Pituitary surgery and radiation - p. 577 25. Medical treatments - p. 579 26. Adrenal surgery - p. 581 27. Overall approach for treatment - p. 582 28. Chapter 18 Nonfunctioning and Gonadotrophin-Secreting Adenomas - p. 599 29. Chapter 19 Thyrotrophin-Secreting Pituitary Adenomas - p. 615 30. Chapter 20 Aggressive Pituitary Adenomas - p. 637 31. Chapter 21 Genetics of Pituitary Adenoma Syndromes - p. 649 32. Chapter 22 Nonpituitary Sellar Masses - p. 661 33. Chapter 23 Pituitary Imaging - p. 677 34. Chapter 24 Pituitary Surgery - p. 723 35. Chapter 25 Radiotherapy in the Management of Pituitary Adenomas - p. 753 36. Index - p. 765 37. Index - Continued - p. 774
